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β-catenin (C-term) Antibody

β-catenin (C-term) Antibody size: 0.1ml 354

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 354
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name&beta, -catenin (C-term) Primary Polyclonal Antibody
Also known as&beta, -catenin (C-term) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigen&beta, -catenin (C-term)
Specificity-catenin (C-term), This is a highly specific antibody against &beta
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Source coli, His-tagged recombinant Human -Catenin (C-terminal fragment) protein purified from E
Gene ID number1499
Swiss ProtP35222
Tested Applications IP, WB
Recommended dilutionsWB (1:2000) IP (1-2 ul)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen APC, AXIN2, Acts as a negative regulator of centrosome cohesion, Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome, CTNNB1 is not ubiquitinated and accumulates in the nucleus, Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML (PubMed:17524503, In the absence of Wnt, In the presence of Wnt ligand, Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization, Involved in the regulation of cell adhesion, Promotes neurogenesis by maintaining sympathetic neuroblasts within the cell cycle (By similarity), PubMed:18077326, PubMed:18086858, PubMed:18957423, PubMed:21262353, PubMed:22155184), PubMed:22647378, PubMed:22699938, forms a complex with AXIN1, leading to activate Wnt responsive genes, where it acts as a coactivator for transcription factors of the TCF/LEF family, Key downstream component of the canonical Wnt signaling pathway
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Beta-catenin, CTNNB1, Catenin beta-1, MRD19, OK/SW-cl, PRO2286, armadillo, 35, CTNNB
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target&beta, -catenin (C-term)
Short name&beta, -catenin (C-term) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name&beta, -catenin (c terminus) (Antibody to)
Alternative techniqueantibodies

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