Name : 14-3-3 sigma Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3853066270
| Long name | ALEXA FLUOR 350 Conjugated, 14-3-3 sigma Polyclonal Antibody |
| Also known as | Anti-14-3-3 sigma PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | 14-3-3 sigma |
| Specificity | This is a highly specific antibody against 14-3-3 sigma |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human 14-3-3 sigma |
| Gene ID Number | 2810 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | 14-3-3 s, 14-3-3 s acts to stimulate the Akt/mTOR signaling pathway by upregulating protein synthesis and cell growth, 14-3-3 s also functions to positively mediate IGF-I-induced cell cycle progression and can bind to a variety of translation initiation factors, 14-3-3 s is able to bind and modify the activity of a large number of proteins, 14-3-3 s positively regulates the tumor suppressor p53 and increases the rate of p53-regulated inhibition of G2/M cell cycle progression, Expressed predominately in stratified squamous keratinising epithelium, HME1 or YWHAS, In response to tumor growth, Multiple isoforms of 14-3-3 s exist due to alternative splicing events, Seven isoforms, When bound to Keratin 17, also known as SFN, comprise this family of signaling intermediates, denoted 14-3-3 b, e, for example, g, h, is a secreted adaptor protein that is involved in regulating both general and specific signaling pathways, mitogenic signaling and cell-cycle checkpoints, notably apoptosis, q and s, stratifin, such as KRT17 (Keratin 17), through recognition of a phosphothreonine or phosphoserine motif, thus controlling mitotic translation, z, 14-3-3 proteins regulate many cellular processes relevant to cancer biology |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | HS1 14-3-3 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | 14-3-3 sigma |
| Short name | 14-3-3 sigma Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, 14-3-3 sigma (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12854 |
| Gene | YWHAQ |
| Long gene name | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
| Synonyms gene name | theta , theta polypeptide protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein |
| Synonyms name | protein tau |
| Locus | 2p25, 1 |
| Discovery year | 1999-08-20 |
| GenBank acession | AF070556 |
| Entrez gene record | 10971 |
| Pubmed identfication | 11080204 |
| RefSeq identity | NM_006826 |
| Classification | 14-3-3 phospho-serine/phospho-threonine binding proteins |
| Havana BLAST/BLAT | OTTHUMG00000013848 |