Filters

14-3-3 sigma Antibody, ALEXA FLUOR 488

14-3-3 sigma Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, 14-3-3 sigma Polyclonal Antibody
Also known asAnti-14-3-3 sigma PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigen14-3-3 sigma
SpecificityThis is a highly specific antibody against 14-3-3 sigma
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human 14-3-3 sigma
Gene ID Number2810
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen 14-3-3 s, 14-3-3 s acts to stimulate the Akt/mTOR signaling pathway by upregulating protein synthesis and cell growth, 14-3-3 s also functions to positively mediate IGF-I-induced cell cycle progression and can bind to a variety of translation initiation factors, 14-3-3 s is able to bind and modify the activity of a large number of proteins, 14-3-3 s positively regulates the tumor suppressor p53 and increases the rate of p53-regulated inhibition of G2/M cell cycle progression, Expressed predominately in stratified squamous keratinising epithelium, HME1 or YWHAS, In response to tumor growth, Multiple isoforms of 14-3-3 s exist due to alternative splicing events, Seven isoforms, When bound to Keratin 17, also known as SFN, comprise this family of signaling intermediates, denoted 14-3-3 b, e, for example, g, h, is a secreted adaptor protein that is involved in regulating both general and specific signaling pathways, mitogenic signaling and cell-cycle checkpoints, notably apoptosis, q and s, stratifin, such as KRT17 (Keratin 17), through recognition of a phosphothreonine or phosphoserine motif, thus controlling mitotic translation, z, 14-3-3 proteins regulate many cellular processes relevant to cancer biology
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms HS1 14-3-3
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the 14-3-3 sigma Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene target14-3-3 sigma
Short name14-3-3 sigma Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, 14-3-3 sigma (Antibody to)
Alternative techniqueantibodies
Identity 12854
Gene YWHAQ
Long gene name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Synonyms gene name theta , theta polypeptide protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein
Synonyms name protein tau
Locus 2p25, 1
Discovery year 1999-08-20
GenBank acession AF070556
Entrez gene record 10971
Pubmed identfication 11080204
RefSeq identity NM_006826
Classification 14-3-3 phospho-serine/phospho-threonine binding proteins
Havana BLAST/BLAT OTTHUMG00000013848

Similar products

Subscribe to our Newsletter