Name : 17-beta-Hydroxysteroid dehydrogenase 4 Antibody (HSD17B4)
Supplier : NJS POLY
Price :389
SKU : GEN7670682562
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | 17-beta-Hydroxysteroid dehydrogenase 4 (HSD17B4) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Titration of the 17-beta-Hydroxysteroid dehydrogenase 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This 17-beta-Hydroxysteroid dehydrogenase 4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | F5HE57 |
| Purity | Antigen affinity |
| Description | In contrast, It was first identified as a 17-beta-estradiol dehydrogenase, Peroxisomal beta-oxidation of fatty acids is catalyzed by 3 enzymes: acyl-CoA oxidase, The D- and L-bifunctional proteins have different substrate specificities, The D-bifunctional protein catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids and also acts in shortening cholesterol for bile acid formation, and 3-ketoacyl-CoA thiolase, the D-bifunctional enzyme with enoyl-CoA-hydratase and D-3-hydroxyacyl-CoA dehydrogenase activity, the L-specific bifunctional protein does not have the latter 2 activities, The HSD17B4 gene encodes an enzyme involved in peroxisomal fatty acid beta-oxidation |
| Immunogen | mouse and rat), An amino acid sequence from the C-terminus of human HSD17B4 (NIMLSQKLQMILKDYAKL) was used as the immunogen for this 17-beta-Hydroxysteroid dehydrogenase 4 antibody (100% homologous in human |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the 17-beta-Hydroxysteroid dehydrogenase 4 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | 17-beta-Hydroxysteroid dehydrogenase 4 (HSD17B4) |
| Short name | 17-beta-Hydroxysteroid dehydrogenase 4 Antibody (HSD17B4) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 17-b-Hydroxysteroid dehydrogenase 4 (Antibody to) (HSD17B4) |
| Alternative technique | antibodies |
| Identity | 5213 |
| Gene | HSD17B4 |
| Long gene name | hydroxysteroid 17-beta dehydrogenase 4 |
| Synonyms gene name | hydroxysteroid (17-beta) dehydrogenase 4 |
| Synonyms | MFE-2 DBP SDR8C1 |
| Synonyms name | 17beta-estradiol dehydrogenase type IV peroxisomal multifunctional protein 2 17-beta-HSD IV 17-beta-hydroxysteroid dehydrogenase 4 D-bifunctional protein, member 1 , peroxisomal D-3-hydroxyacyl-CoA dehydratase 3-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase beta-keto-reductase beta-hydroxyacyl dehydrogenase short chain dehydrogenase/reductase family 8C, 7-alpha |
| Locus | 5q23, 1 |
| Discovery year | 1994-09-14 |
| Entrez gene record | 3295 |
| Pubmed identfication | 8938456 19027726 |
| RefSeq identity | NM_000414 |
| Classification | Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT | OTTHUMG00000128899 |