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17-beta-Hydroxysteroid dehydrogenase 4 Antibody (HSD17B4)

17-beta-Hydroxysteroid dehydrogenase 4 Antibody (HSD17B4) size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigen17-beta-Hydroxysteroid dehydrogenase 4 (HSD17B4)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the 17-beta-Hydroxysteroid dehydrogenase 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis 17-beta-Hydroxysteroid dehydrogenase 4 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #F5HE57
PurityAntigen affinity
Description In contrast, It was first identified as a 17-beta-estradiol dehydrogenase, Peroxisomal beta-oxidation of fatty acids is catalyzed by 3 enzymes: acyl-CoA oxidase, The D- and L-bifunctional proteins have different substrate specificities, The D-bifunctional protein catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids and also acts in shortening cholesterol for bile acid formation, and 3-ketoacyl-CoA thiolase, the D-bifunctional enzyme with enoyl-CoA-hydratase and D-3-hydroxyacyl-CoA dehydrogenase activity, the L-specific bifunctional protein does not have the latter 2 activities, The HSD17B4 gene encodes an enzyme involved in peroxisomal fatty acid beta-oxidation
Immunogen mouse and rat), An amino acid sequence from the C-terminus of human HSD17B4 (NIMLSQKLQMILKDYAKL) was used as the immunogen for this 17-beta-Hydroxysteroid dehydrogenase 4 antibody (100% homologous in human
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the 17-beta-Hydroxysteroid dehydrogenase 4 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target17-beta-Hydroxysteroid dehydrogenase 4 (HSD17B4)
Short name17-beta-Hydroxysteroid dehydrogenase 4 Antibody (HSD17B4)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name17-b-Hydroxysteroid dehydrogenase 4 (Antibody to) (HSD17B4)
Alternative techniqueantibodies
Identity 5213
Gene HSD17B4
Long gene name hydroxysteroid 17-beta dehydrogenase 4
Synonyms gene name hydroxysteroid (17-beta) dehydrogenase 4
Synonyms MFE-2 DBP SDR8C1
Synonyms name 17beta-estradiol dehydrogenase type IV peroxisomal multifunctional protein 2 17-beta-HSD IV 17-beta-hydroxysteroid dehydrogenase 4 D-bifunctional protein, member 1 , peroxisomal D-3-hydroxyacyl-CoA dehydratase 3-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase beta-keto-reductase beta-hydroxyacyl dehydrogenase short chain dehydrogenase/reductase family 8C, 7-alpha
Locus 5q23, 1
Discovery year 1994-09-14
Entrez gene record 3295
Pubmed identfication 8938456 19027726
RefSeq identity NM_000414
Classification Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT OTTHUMG00000128899

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