Name : A4GNT Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9460764990
| Long name | A4GNT Primary Polyclonal Antibody |
| Also known as | A4GNT PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | A4GNT |
| Specificity | This is a highly specific antibody against A4GNT |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human A4GNT |
| Gene ID number | 51146 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Alpha4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAcalpha1-4Galbeta1-R, Alpha4Gn-T and Mucin 6 expression is upregulated in the gastric mucosa of H, Alpha4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity, Alpha4Gn-T is not expressed in peripheral blood cells, It is expressed in stomach and pancreas, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans, as well as in gastric cancer cells, making it a useful biomarker for pancreatic cancer, pylori infection, which suggest the involvement of ?Gn-T in defense against H, 4-N-acetylflucosaminyltransferase (Alpha4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan), Alpha 1, pylori infected patients |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | A4GCT_HUMAN, A4GNT, Alpha 1 4 N acetylglucosaminyltransferase, Alpha-1, Alpha4GnT, EC 2, MGC149493, 1, 4, 4-N-acetylglucosaminyltransferase |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | A4GNT |
| Short name | A4GNT Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | A4GNT (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17968 |
| Gene | A4GNT |
| Long gene name | alpha-1, 4-N-acetylglucosaminyltransferase |
| Synonyms | alpha4GnT |
| Locus | 3q22, 3 |
| Discovery year | 2004-07-12 |
| GenBank acession | AF141315 |
| Entrez gene record | 51146 |
| Pubmed identfication | 10430883 |
| RefSeq identity | NM_016161 |
| Classification | Alpha 1, 4-glycosyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000159820 |