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AASS/LKRSDH Antibody

AASS/LKRSDH Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAASS/LKRSDH Primary Polyclonal Antibody
Also known asAASS/LKRSDH PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAASS/LKRSDH
SpecificityThis is a highly specific antibody against AASS/LKRSDH
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LKRSDH
Gene ID number10157
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen AASS acts as a bifunctional enzyme containing the lysine alpha-ketoglutarate reductase (LKR) and saccharopine dehydrogenase activities that catalyzes the first two steps in lysine degradation, However, It is widely expressed with highest expression in liver and transcription of the AASS gene is induced upon starvation, Mutations in the gene encoding AASS result in various forms familial hyperlysinemias (FH), also designated lysine ketoglutarate reductase (LKR) or saccharopine dehydrogenase (SDH), and variable saccharopinuria, autosomal recessive disorders characterized by hyperlysinemia, is a 926 amino acid protein that exists as a homodimer in the mitochondria, lysinuria, no adverse mental or physical effects have been found in patients with hyperlysinemia, Alpha-aminoadipic semialdehyde synthase (AASS)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AASS_HUMAN, LKR/SDH, LKRSDH, LORSDH, Lysine ketoglutarate reductase, Saccharopine dehydrogenase, Alpha aminoadipic semialdehyde synthase mitochondrial
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAASS/LKRSDH
Short nameAASS/LKRSDH Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAASS/LKRSDH (Antibody to)
Alternative techniqueantibodies
Identity 17366
Gene AASS
Long gene name aminoadipate-semialdehyde synthase
Synonyms LORSDH LKRSDH
Locus 7q31, 32
Discovery year 2002-01-09
GenBank acession AF229180
Entrez gene record 10157
Pubmed identfication 10775527
RefSeq identity NM_005763
Havana BLAST/BLAT OTTHUMG00000157058

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