| Long name | ABCA1 (Ser2054) Primary Polyclonal Antibody |
| Also known as | ABCA1 (Ser2054) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ABCA1 Ser2054 |
| Specificity | This is a highly specific antibody against ABCA1 Ser2054 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser2054 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human ABCA1 around the phosphorylation site of Ser2054 |
| Gene ID number | 19 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ABC genes are divided into seven distinct subfamilies (ABC1, ABC proteins transport various molecules across extra- and intracellular membranes, ALD, GCN20, In humans, MDR/TAP, MRP, Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes, Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency, OABP, This protein is a member of the ABC1 subfamily, White), this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway, The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ABC 1, ABC Transporter 1, ABC1, ABCA 1, ABCA1, ABCA1_HUMAN, ATP binding Cassette 1, ATP binding Cassette Transporter 1, ATP binding cassette sub family A ABC1 member 1, ATP binding cassette sub family A member 1, ATP binding cassette sub-family A member 1, ATP binding cassette transporter A1, ATP-binding Cassette 1, ATP-binding Cassette Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, FLJ14958, HDLDT1, MGC164864, MGC165011, Membrane bound, TD, TGD, p-ABCA1 phospho S2054, ABCA1 phospho S2054 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ABCA1 (Ser2054) |
| Short name | ABCA1 (Ser2054) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | member 1 (Ser2054) (Antibody to), sub-family A (ABC1), adenosine triphosphate-binding cassette |
| Alternative technique | antibodies |
| Alternative to gene target | ABC-1 and ABC1 and CERP and HDLDT1 and TGD, ABCA1 and IDBG-79441 and ENSG00000165029 and 19, ATPase binding, Abca1 and IDBG-147642 and ENSMUSG00000015243 and 11303, BT, Cell surfaces, engulfment and biological process this GO :0007040 and lysosome organization and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008509 and anion transmembrane transporter activity and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0010887 and negative regulation of cholesterol storage and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0015914 and phospholipid transport and biological process this GO :0016197 and endosomal transport and biological process this GO :0016887 and ATPase activity and molecular function this GO :0017127 and cholesterol transporter activity and molecular function this GO :0019905 and syntaxin binding and molecular function this GO :0030139 and endocytic vesicle and cellular component this GO :0030301 and cholesterol transport and biological process this GO :0030819 and positive regulation of cAMP biosynthetic process and biological process this GO :0031267 and small GTPase binding and molecular function this GO :0032367 and intracellular cholesterol transport and biological process this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034185 and apolipoprotein binding and molecular function this GO :0034186 and apolipoprotein A-I binding and molecular function this GO :0034188 and apolipoprotein A-I receptor activity and molecular function this GO :0034364 and high-density lipoprotein particle and cellular component this GO :0034380 and high-density lipoprotein particle assembly and biological process this GO :0034616 and response to laminar fluid shear stress and biological process this GO :0038027 and apolipoprotein A-I-mediated signaling pathway and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042158 and lipoprotein biosynthetic process and biological process this GO :0042493 and response to drug and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043691 and reverse cholesterol transport and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045332 and phospholipid translocation and biological process this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050702 and interleukin-1 beta secretion and biological process this GO :0051117 and ATPase binding and molecular function this GO :0055091 and phospholipid homeostasis and biological process this GO :0055098 and response to low-density lipoprotein particle stimulus and biological process this GO :0060155 and platelet dense granule organization and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0071397 and cellular response to cholesterol and biological process, member 1, sub-family A (ABC1), this GO :0002790 and peptide secretion and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005548 and phospholipid transporter activity and molecular function this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006497 and protein lipidation and biological process this GO :0006911 and pha this GO cytosis, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0005543: phospholipid binding and also this GO :0005548: phospholipid transporter activity and also this GO :0008509: anion transmembrane transporter activity and also this GO :0015485: cholesterol binding and also this GO :0016887: ATPase activity and also this GO :0017127: cholesterol transporter activity and also this GO :0019905: syntaxin binding and also this GO :0031267: small GTPase binding and also this GO :0034185: apolipoprotein binding and also this GO :0034186: apolipoprotein A-I binding and also this GO :0034188: apolipoprotein A-I receptor activity and also this GO :0051117: ATPase binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0005543: phospholipid binding, this GO :0005548: phospholipid transporter activity, this GO :0008509: anion transmembrane transporter activity, this GO :0015485: cholesterol binding, this GO :0016887: ATPase activity, this GO :0017127: cholesterol transporter activity, this GO :0019905: syntaxin binding, this GO :0031267: small GTPase binding, this GO :0034185: apolipoprotein binding, this GO :0034186: apolipoprotein A-I binding, this GO :0034188: apolipoprotein A-I receptor activity, this GO :0051117: ATPase binding, 89249 and IDBG-637291 and ENSBTAG00000020661 and 535379, ATP-binding cassette |
| Identity | 29 |
| Gene | ABCA1 |
| Long gene name | ATP binding cassette subfamily A member 1 |
| Synonyms gene | ABC1 HDLDT1 |
| Synonyms gene name | ATP-binding cassette, member 1 , sub-family A (ABC1) |
| Synonyms | TGD |
| Synonyms name | Tangier disease |
| Locus | 9q31, 1 |
| Discovery year | 2005-03-17 |
| GenBank acession | AJ012376 |
| Entrez gene record | 19 |
| Pubmed identfication | 8088782 10431236 10431237 10431238 |
| RefSeq identity | NM_005502 |
| Classification | ATP binding cassette subfamily A |
| Havana BLAST/BLAT | OTTHUMG00000020417 |
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