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ABCA7 Antibody, ALEXA FLUOR 350

ABCA7 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, ABCA7 Polyclonal Antibody
Also known asAnti-ABCA7 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenABCA7
SpecificityThis is a highly specific antibody against ABCA7
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ABCA7
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen ABCA7, Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, Full-length type I ABCA7 has shown plasma membrane localization, High expression levels of ABCA7 have been reported in myelolymphatic tissues, The cholesterol-responsive transporter, This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization, or for secretion from the body, outside the cell for transport to other organs, peripheral leukocytes, reticuloendothelial cells, spleen and bone marrow, though the complete role of ABCA7 is not yet known, thymus, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum, ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms ABCX
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetABCA7
Short nameABCA7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, member 7 (Antibody to), sub-family A (ABC1), adenosine triphosphate-binding cassette
Alternative techniqueantibodies
Alternative to gene target ABCA-SSN and ABCX, ABCA7 and IDBG-13665 and ENSG00000064687 and 10347, ABCA7 and IDBG-645574 and ENSBTAG00000020766 and 511762, Abca7 and IDBG-171979 and ENSMUSG00000035722 and 27403, Cell surfaces, apolipoprotein A-I receptor activity, member 7, sub-family A (ABC1), this GO :0000139 and this GO lgi membrane and cellular component this GO :0001891 and pha this GO cytic cup and cellular component this GO :0005215 and transporter activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005548 and phospholipid transporter activity and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006909 and pha this GO cytosis and biological process this GO :0007613 and memory and biological process this GO :0009986 and cell surface and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016887 and ATPase activity and molecular function this GO :0017121 and phospholipid scrambling and biological process this GO :0018149 and peptide cross-linking and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032780 and negative regulation of ATPase activity and biological process this GO :0032781 and positive regulation of ATPase activity and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034188 and apolipoprotein A-I receptor activity and molecular function this GO :0034380 and high-density lipoprotein particle assembly and biological process this GO :0034504 and protein localization to nucleus and biological process this GO :0038027 and apolipoprotein A-I-mediated signaling pathway and biological process this GO :0042985 and negative regulation of amyloid precursor protein biosynthetic process and biological process this GO :0043190 and ATP-binding cassette (ABC) transporter complex and cellular component this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :1900223 and positive regulation of beta-amyloid clearance and biological process this GO :1901076 and positive regulation of engulfment of apoptotic cell and biological process this GO :1902430 and negative regulation of beta-amyloid formation and biological process this GO :1902995 and positive regulation of phospholipid efflux and biological process, this GO :0005215: transporter activity, this GO :0005215: transporter activity and also this GO :0005524: ATP binding and also this GO :0005548: phospholipid transporter activity and also this GO :0016887: ATPase activity and also this GO :0034188: apolipoprotein A-I receptor activity, this GO :0005524: ATP binding, this GO :0005548: phospholipid transporter activity, this GO :0016887: ATPase activity, this GO :0034188: apolipoprotein A-I receptor activity, ATP-binding cassette
Identity 37
Gene ABCA7
Long gene name ATP binding cassette subfamily A member 7
Synonyms gene name ATP-binding cassette, member 7 , sub-family A (ABC1)
Locus 19p13, 3
Discovery year 1999-06-11
GenBank acession AF328787
Entrez gene record 10347
RefSeq identity NM_019112
Classification ATP binding cassette subfamily A
Havana BLAST/BLAT OTTHUMG00000167547

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