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ABCD2 Antibody

ABCD2 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenABCD2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000
Intented useThis ABCD2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9UBJ2
PurityAntigen affinity
Description ABC genes are divided into seven distinct subfamilies (ABC1, ABC proteins transport various molecules across extra- and intra-cellular membranes, ALD, All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter, GCN20, MDR/TAP, MRP, Mutations in this gene have been observed in patients with adrenoleukodystrophy, OABP, The function of this peroxisomal membrane protein is unknown, This gene has been identified as a candidate for a modifier gene, This gene is also a candidate for a complement group of Zellweger syndrome, This protein is a member of the ALD subfamily, White), a genetically heterogeneous disorder of peroxisomal biogenesis, a severe demyelinating disease, accounting for the extreme variation among adrenoleukodystrophy phenotypes, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle, The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters
ImmunogenA portion of amino acids 553-582 from the human protein was used as the immunogen for this ABCD2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ABCD2 antibody and store frozen at -20 deg
LocalizationCytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetABCD2
Short nameABCD2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name member 2 (Antibody to), sub-family D (ALD), adenosine triphosphate-binding cassette
Alternative techniqueantibodies
Alternative to gene target ABC39 and ALDL1 and ALDR and ALDRP and hALDR, ABCD2 and IDBG-26995 and ENSG00000173208 and 225, ATPase activity, Abcd2 and IDBG-175455 and ENSMUSG00000055782 and 26874, BT, Plasma membranes, coupled to transmembrane movement of substances, coupled to transmembrane movement of substances and also this GO :0042803: protein homodimerization activity, coupled to transmembrane movement of substances and molecular function this GO :0042760 and very long-chain fatty acid catabolic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0055085 and transmembrane transport and biological process, member 2, sub-family D (ALD), this GO :0000038 and very long-chain fatty acid metabolic process and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005778 and peroxisomal membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006635 and fatty acid beta-oxidation and biological process this GO :0006810 and transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016887 and ATPase activity and molecular function this GO :0032000 and positive regulation of fatty acid beta-oxidation and biological process this GO :0042626 and ATPase activity, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016887: ATPase activity and also this GO :0042626: ATPase activity, this GO :0005524: ATP binding, this GO :0016887: ATPase activity, this GO :0042626: ATPase activity, this GO :0042803: protein homodimerization activity, 526436, 101909154, 87418 and IDBG-633512 and ENSBTAG00000038043 and 100335783, ATP-binding cassette
Identity 66
Gene ABCD2
Long gene name ATP binding cassette subfamily D member 2
Synonyms gene ALDL1
Synonyms gene name ATP-binding cassette, member 2 , sub-family D (ALD)
Synonyms ALDR ALDRP
Locus 12q12
Discovery year 1997-10-10
GenBank acession U28150
Entrez gene record 225
Pubmed identfication 8577752
RefSeq identity NM_005164
Classification ATP binding cassette subfamily D
Havana BLAST/BLAT OTTHUMG00000169337

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