Name : ABCD2 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN2467060308
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | ABCD2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IHC, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Intented use | This ABCD2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9UBJ2 |
| Purity | Antigen affinity |
| Description | ABC genes are divided into seven distinct subfamilies (ABC1, ABC proteins transport various molecules across extra- and intra-cellular membranes, ALD, All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter, GCN20, MDR/TAP, MRP, Mutations in this gene have been observed in patients with adrenoleukodystrophy, OABP, The function of this peroxisomal membrane protein is unknown, This gene has been identified as a candidate for a modifier gene, This gene is also a candidate for a complement group of Zellweger syndrome, This protein is a member of the ALD subfamily, White), a genetically heterogeneous disorder of peroxisomal biogenesis, a severe demyelinating disease, accounting for the extreme variation among adrenoleukodystrophy phenotypes, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle, The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters |
| Immunogen | A portion of amino acids 553-582 from the human protein was used as the immunogen for this ABCD2 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ABCD2 antibody and store frozen at -20 deg |
| Localization | Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | ABCD2 |
| Short name | ABCD2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | member 2 (Antibody to), sub-family D (ALD), adenosine triphosphate-binding cassette |
| Alternative technique | antibodies |
| Alternative to gene target | ABC39 and ALDL1 and ALDR and ALDRP and hALDR, ABCD2 and IDBG-26995 and ENSG00000173208 and 225, ATPase activity, Abcd2 and IDBG-175455 and ENSMUSG00000055782 and 26874, BT, Plasma membranes, coupled to transmembrane movement of substances, coupled to transmembrane movement of substances and also this GO :0042803: protein homodimerization activity, coupled to transmembrane movement of substances and molecular function this GO :0042760 and very long-chain fatty acid catabolic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0055085 and transmembrane transport and biological process, member 2, sub-family D (ALD), this GO :0000038 and very long-chain fatty acid metabolic process and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005778 and peroxisomal membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006635 and fatty acid beta-oxidation and biological process this GO :0006810 and transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016887 and ATPase activity and molecular function this GO :0032000 and positive regulation of fatty acid beta-oxidation and biological process this GO :0042626 and ATPase activity, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016887: ATPase activity and also this GO :0042626: ATPase activity, this GO :0005524: ATP binding, this GO :0016887: ATPase activity, this GO :0042626: ATPase activity, this GO :0042803: protein homodimerization activity, 526436, 101909154, 87418 and IDBG-633512 and ENSBTAG00000038043 and 100335783, ATP-binding cassette |
| Identity | 66 |
| Gene | ABCD2 |
| Long gene name | ATP binding cassette subfamily D member 2 |
| Synonyms gene | ALDL1 |
| Synonyms gene name | ATP-binding cassette, member 2 , sub-family D (ALD) |
| Synonyms | ALDR ALDRP |
| Locus | 12q12 |
| Discovery year | 1997-10-10 |
| GenBank acession | U28150 |
| Entrez gene record | 225 |
| Pubmed identfication | 8577752 |
| RefSeq identity | NM_005164 |
| Classification | ATP binding cassette subfamily D |
| Havana BLAST/BLAT | OTTHUMG00000169337 |