Name : ABCG2 Antibody (BCRP)
Supplier : NJS POLY
Price :199
SKU : GEN7080626686
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | ABCG2 (BCRP) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IF, IHC, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the ABCG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This ABCG2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9UNQ0 |
| Purity | Purified |
| Description | ABC genes are divided into seven distinct subfamilies (ABC1, ABC proteins transport various molecules across extra- and intra-cellular membranes, ALD, Alternatively referred to as a breast cancer resistance protein, GCN20, It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure, MDR/TAP, MRP, OABP, Significant expression of this protein has been observed in the placenta, This protein is a member of the White subfamily, White), this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance, which may suggest a potential role for this molecule in placenta tissue, ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters |
| Immunogen | A portion of amino acids 305-335 from the human protein was used as the immunogen for this ABCG2 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ABCG2 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | ABCG2 (BCRP) |
| Short name | ABCG2 Antibody (BCRP) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ABCG2 (Antibody to) (BCRP) |
| Alternative technique | antibodies |
| Identity | 74 |
| Gene | ABCG2 |
| Long gene name | ATP binding cassette subfamily G member 2 (Junior blood group) |
| Synonyms gene name | ATP-binding cassette, member 2 (Junior blood group) , member 2 ATP-binding cassette, sub-family G (WHITE), sub-family G (WHITE) |
| Synonyms | EST157481 MXR BCRP ABCP CD338 |
| Locus | 4q22, 1 |
| Discovery year | 1999-10-26 |
| GenBank acession | AF103796 |
| Entrez gene record | 9429 |
| Pubmed identfication | 8894702 9861027 |
| RefSeq identity | NM_004827 |
| Classification | CD molecules Blood group antigens ATP binding cassette subfamily G |
| Havana BLAST/BLAT | OTTHUMG00000130601 |
| Locus Specific Databases | LRG_823 |