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ABI1 Antibody

ABI1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameABI1 Primary Polyclonal Antibody
Also known asABI1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenABI1
SpecificityThis is a highly specific antibody against ABI1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range140-190/508
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ABI1
Gene ID number10006
Swiss ProtQ8IZP0
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex, In brain, In vitro, Involved in cytoskeletal reorganization and EGFR signaling, May play a role in regulation of EGF-induced Erk pathway activation, Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level, Regulates ABL1/c-Abl-mediated phosphorylation of ENAH, Together with EPS8 participates in transduction of signals from Ras to Rac, a trimeric complex of ABI1, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons, May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ABI-1, ABI1, ABLBP4, Abelson interactor 1, Abl interactor 1, Abl-binding protein 4, Eps8 SH3 domain-binding protein, Eps8-binding protein, NAP1BP, Nap1-binding protein, SSH3BP, SSH3BP1, Spectrin SH3 domain-binding protein 1, E3B1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetABI1
Short nameABI1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameABI1 (Antibody to)
Alternative techniqueantibodies
Identity 11320
Gene ABI1
Long gene name abl interactor 1
Synonyms gene SSH3BP1
Synonyms gene name spectrin SH3 domain binding protein 1 abl-interactor 1
Synonyms E3B1 ABI-1
Locus 10p12, 1
Discovery year 1999-05-17
GenBank acession U87166
Entrez gene record 10006
Pubmed identfication 9593709 9010225
RefSeq identity NM_005470
Havana BLAST/BLAT OTTHUMG00000017848

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