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ABI1 Antibody, Biotin Conjugated

ABI1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, ABI1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenABI1
SpecificityThis is a highly specific antibody against ABI1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range140-190/508
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human ABI1
Gene ID number10006
Swiss ProtQ8IZP0
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex, In brain, In vitro, Involved in cytoskeletal reorganization and EGFR signaling, May play a role in regulation of EGF-induced Erk pathway activation, Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level, Regulates ABL1/c-Abl-mediated phosphorylation of ENAH, Together with EPS8 participates in transduction of signals from Ras to Rac, a trimeric complex of ABI1, seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons, May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms E3B1 ABI-1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetABI1 Conjugated
Short name Conjugated, ABI1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ABI1 (Antibody to)
Alternative techniqueantibodies
Identity 11320
Gene ABI1
Long gene name abl interactor 1
Synonyms gene SSH3BP1
Synonyms gene name spectrin SH3 domain binding protein 1 abl-interactor 1
Locus 10p12, 1
Discovery year 1999-05-17
GenBank acession U87166
Entrez gene record 10006
Pubmed identfication 9593709 9010225
RefSeq identity NM_005470
Havana BLAST/BLAT OTTHUMG00000017848

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