| Long name | ACE2 Primary Polyclonal Antibody |
| Also known as | ACE2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ACE2 |
| Specificity | This is a highly specific antibody against ACE2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 599-649/805 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ACE2 |
| Gene ID number | 59272 |
| Swiss Prot | Q9BYF1 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Pig, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency, In case of human coronaviruses SARS and HCoV-NL63 infections, May be an important regulator of heart function, a peptide of unknown function, a vasodilator, and angiotensin II to angiotensin 1-7, serve as functional receptor for the spike glycoprotein of both coronaviruses, Carboxypeptidase which converts angiotensin I to angiotensin 1-9 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ACE-related carboxypeptidase, ACE2, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, Metalloprotease MPROT15, UNQ868/PRO1885, ACEH |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ACE2 |
| Short name | ACE2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | ACE2 and IDBG-46534 and ENSG00000130234 and 59272, ACE2 and IDBG-638902 and ENSBTAG00000034402 and 101908244, Ace2 and IDBG-184519 and ENSMUSG00000015405 and 70008, Extracellular, peptide binding, this GO :0001618 and virus receptor activity and molecular function this GO :0001817 and regulation of cytokine production and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0002003 and angiotensin maturation and biological process this GO :0002005 and angiotensin catabolic process in blood and biological process this GO :0003051 and angiotensin-mediated drinking behavior and biological process this GO :0003081 and regulation of systemic arterial blood pressure by renin-angiotensin and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004180 and carboxypeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008241 and peptidyl-dipeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0009615 and response to virus and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017046 and peptide hormone binding and molecular function this GO :0019229 and regulation of vasoconstriction and biological process this GO :0032800 and receptor biosynthetic process and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042277 and peptide binding and molecular function this GO :0042312 and regulation of vasodilation and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0046718 and viral entry into host cell and biological process this GO :0046813 and receptor-mediated virion attachment to host cell and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process, this GO :0001618: virus receptor activity, this GO :0001618: virus receptor activity and also this GO :0001948: glycoprotein binding and also this GO :0004175: endopeptidase activity and also this GO :0004180: carboxypeptidase activity and also this GO :0005515: protein binding and also this GO :0008237: metallopeptidase activity and also this GO :0008241: peptidyl-dipeptidase activity and also this GO :0008270: zinc ion binding and also this GO :0017046: peptide hormone binding and also this GO :0042277: peptide binding, this GO :0001948: glycoprotein binding, this GO :0004175: endopeptidase activity, this GO :0004180: carboxypeptidase activity, this GO :0005515: protein binding, this GO :0008237: metallopeptidase activity, this GO :0008241: peptidyl-dipeptidase activity, this GO :0008270: zinc ion binding, this GO :0017046: peptide hormone binding, this GO :0042277: peptide binding, 509235, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| Identity | 13557 |
| Gene | ACE2 |
| Long gene name | angiotensin I converting enzyme 2 |
| Synonyms gene name | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
| Synonyms name | peptidyl-dipeptidase A |
| Locus | Xp22, 2 |
| Discovery year | 2000-09-25 |
| GenBank acession | AF291820 |
| Entrez gene record | 59272 |
| Pubmed identfication | 10969042 |
| Havana BLAST/BLAT | OTTHUMG00000021177 |
| Locus Specific Databases | Mental Retardation database |
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