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Acinus (Ser1180) Antibody, ALEXA FLUOR 594

Acinus (Ser1180) Antibody, ALEXA FLUOR 594 size: 100ul 350

Price 350
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, Acinus (Ser1180) Polyclonal Antibody
Also known asAnti-Acinus Ser1180 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAcinus Ser1180
SpecificityThis is a highly specific antibody against Acinus Ser1180
ModificationPhosphorylation
Modification SiteSer1180
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1150-1200/1341
Subcellular locationNucleus
SourceKLH conjugated synthetic phosphopeptide derived from human Acinus around the phosphorylation site of Ser1180
Gene ID Number22985
Swiss ProtQ9UKV3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen ACIN1 confers RNA-binding to the complex, Component of the ASAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets, Induces apoptotic chromatin condensation after activation by CASP3, Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes), Regulates cyclin A1, The ASAP complex can inhibit RNA processing during in vitro splicing reactions, The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis, The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism, but not cyclin A2, expression in leukemia cells, specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S), the activity is different from the established EJC assembly and function, Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms ACIN1, ACINUS, Apoptotic chromatin condensation inducer in the nucleus, KIAA0670, fSAP152, ACN
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetAcinus (Ser1180)
Short nameAcinus (Ser1180) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Acinus (Ser1180) (Antibody to)
Alternative techniqueantibodies

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