Name : Aconitase 1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6492315384
| Long name | Aconitase 1 Primary Polyclonal Antibody |
| Also known as | Aconitase 1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Aconitase 1 |
| Specificity | This is a highly specific antibody against Aconitase 1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Aconitase 1/IRP-1 |
| Gene ID number | 48 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells, IRPs respond to stress mediators, Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins, They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs), also known as iron responsive element-binding protein-1 and -2 (IREâ, cytokines and hydrogen peroxide, including nitrogen monoxide, iron concentration and signaling factors, iron regulatory protein-1 and -2 (IRP-1 and -2), &euro, &ldquo, BP-1 and -2) or aconitase 1 and 2, Iron metabolism is essential for sustaining mammalian homeostasis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ACO1, ACOC_HUMAN, ACONS, Aconitase, Aconitase 1 soluble, Aconitase1, Aconitate hydratase, Citrate hydro lyase, Citrate hydro-lyase, Cytoplasmic aconitate hydratase, Ferritin repressor protein, IRE BP 1, IRE-BP 1, IREB 1, IREB1, IREBP, IREBP1, IRP 1, IRP1, Iron regulatory protein 1, Iron responsive element binding protein 1, Iron-responsive element-binding protein 1, ACO 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Aconitase 1 |
| Short name | Aconitase 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Aconitase 1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 117 |
| Gene | ACO1 |
| Long gene name | aconitase 1 |
| Synonyms gene | IREB1 |
| Synonyms gene name | aconitase 1, soluble |
| Synonyms | IRP1 IREBP |
| Synonyms name | aconitate hydratase, cytoplasmic soluble aconitase cytosplasmic aconitase |
| Locus | 9p21, 1 |
| Discovery year | 1989-01-01 |
| GenBank acession | M58510 |
| Entrez gene record | 48 |
| Pubmed identfication | 2172968 2771641 |
| RefSeq identity | NM_002197 |
| Havana BLAST/BLAT | OTTHUMG00000019740 |