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Activated Notch1 Antibody, ALEXA FLUOR 555

Activated Notch1 Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, Activated Notch1 Polyclonal Antibody
Also known asAnti-Neurogenic locus notch homolog protein 1 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenNeurogenic locus notch homolog protein 1
SpecificityThis is a highly specific antibody against Neurogenic locus notch homolog protein 1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1754-1780/2555
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Notch 1 intracellular domain
Gene ID Number4851
Swiss ProtP46531
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Affects the implementation of differentiation, During cerebellar development, Important for follicular differentiation and possibly cell fate selection within the follicle, Involved in angiogenesis, Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO), Involved in the maturation of both CD4+ and CD8+ cells in the thymus, Jagged2 and Delta1 to regulate cell-fate determination, May be involved in mesoderm development, May enhance HIF1A function by sequestering HIF1AN away from HIF1A, May play an essential role in postimplantation development, Represses neuronal and myogenic differentiation, Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting, probably in some aspect of cell specification and/or differentiation, proliferation and apoptotic programs, somite formation and neurogenesis, Functions as a receptor for membrane-bound ligands Jagged1
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms AOS5, AOVD1, NOTCH1, Neurogenic locus notch homolog protein 1, Notch 1, TAN1, Translocation-associated notch protein TAN-1, hN1
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetActivated Notch1
Short nameActivated Notch1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, Activated notch 1 (Antibody to)
Alternative techniqueantibodies

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