| Alternative name1 | AICDA, ARP2, Activation-induced Deaminase, CDA2, HIGM2, Integrated Into Burkitt's Lymphoma Line Ramos), Anti-Activation-induced Cytidine Deaminase (AID |
| Alternative name2 | AICDA, ARP2, Activation-induced Deaminase, CDA2, HIGM2, Integrated Into Burkitt's Lymphoma Line Ramos), Activation-induced Cytidine Deaminase (AID |
| Alternative name3 | AICDA, ARP2, Activation-induced Deaminase, CDA2, HIGM2, IntegRattus norvegicused Into Burkitt's Lymphoma Line Ramos), Activation-induced Cytidine Deaminase (AID |
| Alternative name4 | Activation-induced Cytidine Deaminase |
| Alternative name5 | AICDA, ARP2, Activation-induced Deaminase, CDA2, HIGM2, Integrated Into Burkitt's Lymphoma Line Ramos), Anti -Activation-induced Cytidine Deaminase (AID |
| Other names | AID, N/A, OTTHUMP00000239182, OTTHUMP00000239185, OTTHUMP00000239186, activation-induced cytidine deaminase, activation-induced cytidine deaminase, cytidine aminohydrolase, integrated into Burkitt's lymphoma cell line Ramos, activation-induced cytidine deaminase |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | AICDA, AID, AID, ARP2, CDA2, HIGM2, AICDA |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | N/A |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Goat |
| Species reactivity | Human |
| Specificity and cross-reactivity | Spleen and Tonsil lysates (calculated MW of 24, 0kD according to NP_065712, 1), Recognizes human AID at ~26kD in Human Lymph Node |
| Purification method | Affinity Purified by immunoaffinity chromatography |
| Form/Appearance | 0, 0, pH 7, 02% sodium azide, 2, 5% BSA, Supplied as a liquid in Tris-saline |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB), ELISA (EL/EIA) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target | AICDA, ARP2, Activation Deaminase, CDA2, HIGM2, Integrated Into Burkitt's Lymphoma Line Ramos), Activation Cytidine Deaminase (AID |
| Short name | AICDA, ARP2, Activation-induced Deaminase, CDA2, HIGM2, Integrated Into Burkitt's Lymphoma Line Ramos), Activation-induced Cytidine Deaminase (AID |
| Alternative name | ARP2, Activation-induced Deaminase, CDA2, HIGM2, Integrated Into Burkitt's Lymphoma Line Ramos), activation-induced cytidine deaminase, Activation-induced Cytidine Deaminase (AID |
| Alternative technique | kits |
| Alternative to gene target | AICDA and IDBG-17253 and ENSG00000111732 and 57379, Aicda and IDBG-185563 and ENSMUSG00000040627 and 11628, BT, acting on carbon-nitrogen (but not peptide) bonds, acting on carbon-nitrogen (but not peptide) bonds, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, in cyclic amidines, in cyclic amidines, in cyclic amidines and molecular function this GO :0030183 and B cell differentiation and biological process this GO :0045087 and innate immune response and biological process this GO :0045190 and isotype switching and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0080111 and DNA demethylation and biological process this GO :0090310 and negative regulation of methylation-dependent chromatin silencing and biological process, nuclei, this GO :0000178 and exosome (RNase complex) and cellular component this GO :0003824 and catalytic activity and molecular function this GO :0004126 and cytidine deaminase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006397 and mRNA processing and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009972 and cytidine deamination and biological process this GO :0016445 and somatic diversification of immunoglobulins and biological process this GO :0016446 and somatic hypermutation of immunoglobulin genes and biological process this GO :0016814 and hydrolase activity, this GO :0003824: catalytic activity, this GO :0003824: catalytic activity and also this GO :0004126: cytidine deaminase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016814: hydrolase activity, this GO :0004126: cytidine deaminase activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016814: hydrolase activity, 56893 and IDBG-639763 and ENSBTAG00000018849 and 539888, activation-induced cytidine deaminase |
| Identity | 13203 |
| Gene | AICDA |
| Long gene name | activation induced cytidine deaminase |
| Synonyms gene name | activation-induced cytidine deaminase |
| Synonyms | HIGM2 CDA2 ARP2 AID |
| Locus | 12p13, 31 |
| Discovery year | 2000-09-19 |
| GenBank acession | AB040430 |
| Entrez gene record | 57379 |
| RefSeq identity | NM_020661 |
| Classification | Apolipoprotein B mRNA editing enzyme catalytic subunits |
| Havana BLAST/BLAT | OTTHUMG00000168676 |
| Locus Specific Databases | AICDA base: Mutation registry for Aid deficiency LRG_17 |
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