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ACTL6A Recombinant Protein

ACTL6A Recombinant Protein size: 0.05 mg 383

Supplier PROSCIENCE
Price 383
Size 0.05 mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
About recombinant protein <, Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A, NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage, Required for maximal ATPase activity of SMARCA4/BRG1 and for association of the SMARCA4/BRG1 containing remodelling complex BAF with chromatin/nuclear matrix, This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription, Together with beta-actin, and DNA repair, and for the association of the BAF complex with chromatin/matrix, apoptosis, cerevisiae and Drosophila, including vesicular transport, it is required for maximal ATPase activity of BRG1, nuclear migration and chromatin remodeling, spindle orientation, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression, tumor suppressor mediated growth arrest and replicative senescence, which is functionally related to SWI/SNF complex in S, /b>, : Involved in transcriptional activation and repression of select genes by chromatin remodelling (alteration of DNA-nucleosome topology), FUNCTION<, The ARPs are involved in diverse cellular processes, b>
Other name of the recombinant 53 kDa BRG1-associated factor A, ACTL6, ARPN-BETA, Actin-like protein 6A, BAF53, BAF53A, INO80K, Arp4
Recombinant in coli, E
SEQUENCE 1-429, aa
Activitynot available
Use of recmbinant ELISA, MS, This recombinant protein can be used for WB
Protein is used in MS, WB, E
Suspention medium 0, 0, pH 8, /sub>, 002% NaN<, 1% Triton X-100, 10 mM Tris, 3<, sub>
Keep at Avoid freeze/thaw cycles, When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature, #730, C, Store in working aliquots at -70&
Rec. PROTEIN GI#4757718
Accession nrNP_004292
KDa of reombinant3 kDa (Calculated), 49
Pureity95%
AboutFor research use only
Protein's originHuman
NCBI ID86
Gene nameactin-like 6A
Source proteins, Recombinants or rec
UniprotO96019
Grouprecombinants
Gene targetACTL6A Protein
Gene symbolACTL6A
Short nameACTL6A Recombinant Protein
Technique E, coli recombinant proteins are , proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli
Alternative nameACTL6A recombinant Protein
Alternative techniquerec

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