| Category | Antibody |
| Concentration | pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | ACVR1 |
| Host animal | Goat (Capra aegagrus hircus) |
| Clonality | Polyclonal (goat origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA (peptide), IHC, WB |
| Recommended dilutions | 3-1ug/ml, ELISA (peptide) LOD: 1:128000, Immunohistochemistry (FFPE): 4-6ug/ml, Western blot: 0 |
| Notes | Optimal dilution of the ACVR1 antibody should be determined by the researcher |
| Intented use | This ACVR1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID # | 90 |
| Purity | Antigen affinity |
| Description | type I, Additional name(s) for this target protein: Activin A receptor |
| Immunogen | Amino acids RKFKRRNQERLNPRD were used as the immunogen for this ACVR1 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the ACVR1 antibody at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | ACVR1 |
| Short name | ACVR1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | classification I (Antibody to), activin A receptor |
| Alternative technique | antibodies |
| Alternative to gene target | ACTRI and ACVR1A and ACVRLK2 and ALK2 and FOP and SKR1 and TSRI, ACVR1 and IDBG-641620 and ENSBTAG00000011909 and 338068, ACVR1 and IDBG-72930 and ENSG00000115170 and 90, Acvr1 and IDBG-172102 and ENSMUSG00000026836 and 11477, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0048179 and activin receptor complex and cellular component this GO :0048185 and activin binding and molecular function this GO :0048641 and regulation of skeletal muscle tissue development and biological process this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0060037 and pharyngeal system development and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :0060923 and cardiac muscle cell fate commitment and biological process this GO :0061445 and endocardial cushion cell fate commitment and biological process this GO :0071385 and cellular response to glucocorticoid stimulus and biological process this GO :2000017 and positive regulation of determination of dorsal identity and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, Plasma membranes, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001655 and urogenital system development and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001702 and gastrulation with mouth forming second and biological process this GO :0001707 and mesoderm formation and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0002526 and acute inflammatory response and biological process this GO :0003143 and embryonic heart tube morphogenesis and biological process this GO :0003183 and mitral valve morphogenesis and biological process this GO :0003289 and atrial septum primum morphogenesis and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004675 and transmembrane receptor protein serine/threonine kinase activity and molecular function this GO :0004702 and receptor signaling protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005025 and transforming growth factor beta receptor activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004675: transmembrane receptor protein serine/threonine kinase activity and also this GO :0004702: receptor signaling protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005024: transforming growth factor beta-activated receptor activity and also this GO :0005025: transforming growth factor beta receptor activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004675: transmembrane receptor protein serine/threonine kinase activity, this GO :0004702: receptor signaling protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005024: transforming growth factor beta-activated receptor activity, this GO :0005025: transforming growth factor beta receptor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016361: activin receptor activity, this GO :0016772: transferase activity, this GO :0017046: peptide hormone binding, this GO :0019838: growth factor binding, this GO :0042803: protein homodimerization activity, this GO :0046332: SMAD binding, this GO :0046872: metal ion binding, this GO :0048185: activin binding, this GO :0050431: transforming growth factor beta binding, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017046: peptide hormone binding and also this GO :0019838: growth factor binding and also this GO :0042803: protein homodimerization activity and also this GO :0046332: SMAD binding and also this GO :0046872: metal ion binding and also this GO :0048185: activin binding and also this GO :0050431: transforming growth factor beta binding, transferring phosphorus-containing groups and molecular function this GO :0017046 and peptide hormone binding and molecular function this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030278 and regulation of ossification and biological process this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0032924 and activin receptor signaling pathway and biological process this GO :0032926 and negative regulation of activin receptor signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045177 and apical part of cell and cellular component this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045893 and positive regulation of transcription, transforming growth factor beta receptor activity, type I, type I, type I, type I and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016361: activin receptor activity, type I and also this GO :0016772: transferase activity, type I and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007178 and transmembrane receptor protein serine/threonine kinase signaling pathway and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007281 and germ cell development and biological process this GO :0007368 and determination of left/right symmetry and biological process this GO :0007369 and gastrulation and biological process this GO :0007498 and mesoderm development and biological process this GO :0007507 and heart development and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0016020 and membrane and cellular component this GO :0016361 and activin receptor activity, type I and molecular function this GO :0016772 and transferase activity, activin A receptor |
| Identity | 171 |
| Gene | ACVR1 |
| Long gene name | activin A receptor type 1 |
| Synonyms gene | ACVRLK2 |
| Synonyms gene name | activin A receptor, type I |
| Synonyms | SKR1 ALK2 ACVR1A |
| Locus | 2q24, 1 |
| Discovery year | 1994-01-10 |
| Entrez gene record | 90 |
| Pubmed identfication | 8397373 |
| RefSeq identity | NM_001105 |
| Classification | Type 1 receptor serine/threonine kinases |
| Havana BLAST/BLAT | OTTHUMG00000131967 |
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