| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | ADA / Adenosine deaminase |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (FFPE): 0, Western blot: 0 |
| Notes | Optimal dilution of the Adenosine deaminase antibody should be determined by the researcher |
| Intented use | This Adenosine deaminase antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P00813 |
| Purity | Antigen affinity |
| Description | ADA association has also been observed with epithelial cell differentiation, ADA in humans is involved in the development and maintenance of the immune system, Adenosine deaminase deficiency leads to pulmonary fibrosis, However, It has also been proposed that ADA, It has also been recognized that adenosine deaminase protein and activity is upregulated in mouse hearts that overexpress HIF-1 alpha, Primarily, and gestation maintenance, in addition to adenosine breakdown, neurotransmission, or ADA) is an enzyme involved in purine metabolism, stimulates release of excitatory amino acids and is necessary to the coupling of A1 adenosine receptors and heterotrimeric G proteins, suggesting that chronic exposure to high levels of adenosine can exacerbate inflammation responses rather than suppressing them, which in part explains the attenuated levels of adenosine in HIF-1 alpha expressing hearts during ischemic stress, Adenosine deaminase (also known as adenosine aminohydrolase |
| Immunogen | Amino acids Q135-L363 of the human protein were used as the immunogen for the Adenosine deaminase antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Adenosine deaminase antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | cell membrane, Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | ADA / Adenosine deaminase |
| Short name | ADA Antibody / Adenosine deaminase |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | adenosine deaminase (Antibody to) / Adenosine deaminase |
| Alternative technique | antibodies |
| Alternative to gene target | ADA and IDBG-642808 and ENSBTAG00000005280 and 280712, ADA and IDBG-76830 and ENSG00000196839 and 100, Ada and IDBG-211962 and ENSMUSG00000017697 and 11486, Extracellular, deaminase activity, non-REM sleep and biological process this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043101 and purine-containing compound salvage and biological process this GO :0043103 and hypoxanthine salvage and biological process this GO :0043278 and response to morphine and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045187 and regulation of circadian sleep/wake cycle, sleep and biological process this GO :0045580 and regulation of T cell differentiation and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0045987 and positive regulation of smooth muscle contraction and biological process this GO :0046061 and dATP catabolic process and biological process this GO :0046101 and hypoxanthine biosynthetic process and biological process this GO :0046103 and inosine biosynthetic process and biological process this GO :0046111 and xanthine biosynthetic process and biological process this GO :0046638 and positive regulation of alpha-beta T cell differentiation and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048541 and Peyer's patch development and biological process this GO :0048566 and embryonic digestive tract development and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0050862 and positive regulation of T cell receptor signaling pathway and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0055086 and nucleobase-containing small molecule metabolic process and biological process this GO :0060169 and negative regulation of adenosine receptor signaling pathway and biological process this GO :0060205 and cytoplasmic membrane-bounded vesicle lumen and cellular component this GO :0060407 and negative regulation of penile erection and biological process this GO :0070244 and negative regulation of thymocyte apoptotic process and biological process this GO :0070256 and negative regulation of mucus secretion and biological process, this GO :0001666 and response to hypoxia and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001821 and histamine secretion and biological process this GO :0001829 and trophectodermal cell differentiation and biological process this GO :0001883 and purine nucleoside binding and molecular function this GO :0001889 and liver development and biological process this GO :0001890 and placenta development and biological process this GO :0002314 and germinal center B cell differentiation and biological process this GO :0002636 and positive regulation of germinal center formation and biological process this GO :0002686 and negative regulation of leukocyte migration and biological process this GO :0002906 and negative regulation of mature B cell apoptotic process and biological process this GO :0004000 and adenosine deaminase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006144 and purine nucleobase metabolic process and biological process this GO :0006154 and adenosine catabolic process and biological process this GO :0006157 and deoxyadenosine catabolic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007568 and aging and biological process this GO :0008152 and metabolic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009168 and purine ribonucleoside monophosphate biosynthetic process and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010460 and positive regulation of heart rate and biological process this GO :0016020 and membrane and cellular component this GO :0019239 and deaminase activity and molecular function this GO :0030054 and cell junction and cellular component this GO :0030324 and lung development and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0032261 and purine nucleotide salvage and biological process this GO :0032839 and dendrite cytoplasm and cellular component this GO :0033089 and positive regulation of T cell differentiation in thymus and biological process this GO :0033197 and response to vitamin E and biological process this GO :0033632 and regulation of cell-cell adhesion mediated by integrin and biological process this GO :0042110 and T cell activation and biological process this GO :0042323 and negative regulation of circadian sleep/wake cycle, this GO :0001883: purine nucleoside binding, this GO :0001883: purine nucleoside binding and also this GO :0004000: adenosine deaminase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0019239: deaminase activity, this GO :0004000: adenosine deaminase activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0019239: deaminase activity, adenosine deaminase |
| Identity | 186 |
| Gene | ADA |
| Long gene name | adenosine deaminase |
| Locus | 20q13, 12 |
| Discovery year | 1986-01-01 |
| GenBank acession | X02994 |
| Entrez gene record | 100 |
| Pubmed identfication | 6198240 6090454 |
| RefSeq identity | NM_000022 |
| Classification | Adenosine deaminase family |
| Havana BLAST/BLAT | OTTHUMG00000033081 |
| Locus Specific Databases | ADAbase: Mutation registry for Adenosine Deaminase Deficiency LRG_16 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue