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ADAM12 Antibody

ADAM12 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameADAM12 Primary Polyclonal Antibody
Also known asADAM12 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenADAM12
SpecificityThis is a highly specific antibody against ADAM12
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAM12/MLTN
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ADAM 12 (Meltrin-a) is produced as 2 differentially spliced isoforms, ADAM proteins possess a signal-domain, ADAMs are expressed in brain, Zn2+ dependent proteases that are involved in cell-cell, a 718 amino acid secreted form (ADAM12S) and a 881 amino acid membrane-bound form (ADAM12L), a cysteine-rich region, a disintegrin domain (Integrin ligand), a metalloprotease domain, a pro-domain, a transmembrane domain and a cytoplasmic tail (1-3), adhesion, an epidermal growth factor-like domain, and catalyze proteolysis, and intracellular signaling (3), and is involved in egg-sperm fusion (4-6), and modulation of the neurogenic function of Notch and Delta (1-3), and muscle, bone, breast, cell-matrix interface related processes including fertilization, epididymis, fusion, glycosylated, heart, liver, lung, muscle fusion, ovary, placenta, secretion of TNF?(tumor necrosis factor ?, testis, ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names A disintegrin and metalloproteinase domain 12, A disintegrin and metalloproteinase domain 12, ADA12_HUMAN, ADAM 12, ADAM metallopeptidase domain 12, ADAM12, Disintegrin and metalloproteinase domain-containing protein 12, MCMP, MCMPMltna, MCMPMltna, MLTN, MLTNA, Meltrin alpha, Meltrin-alpha, OTTHUMP00000046766, MLTN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetADAM12
Short nameADAM12 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameADAM metallopeptidase domain 12 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ADAM12 and IDBG-93032 and ENSG00000148848 and 8038, ADAM12-OT1 and CAR10 and MCMP and MCMPMltna and MLTN and MLTNA, Adam12 and IDBG-211287 and ENSMUSG00000054555 and 11489, BT, Extracellular, SH3 domain binding, this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0007155 and cell adhesion and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007520 and myoblast fusion and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0017124 and SH3 domain binding and molecular function, this GO :0004222: metalloendopeptidase activity, this GO :0004222: metalloendopeptidase activity and also this GO :0005515: protein binding and also this GO :0008237: metallopeptidase activity and also this GO :0008270: zinc ion binding and also this GO :0017124: SH3 domain binding, this GO :0005515: protein binding, this GO :0008237: metallopeptidase activity, this GO :0008270: zinc ion binding, this GO :0017124: SH3 domain binding, 29890 and IDBG-640937 and ENSBTAG00000012444 and 407229, ADAM metallopeptidase domain 12
Identity 190
Gene ADAM12
Long gene name ADAM metallopeptidase domain 12
Synonyms gene name a disintegrin and metalloproteinase domain 12 (meltrin alpha)
Synonyms MCMPMltna MLTN
Synonyms name meltrin alpha
Locus 10q26, 2
Discovery year 1998-12-01
GenBank acession AF023476
Entrez gene record 8038
Pubmed identfication 9417060 18342566
Classification ADAM metallopeptidase domain containing
Havana BLAST/BLAT OTTHUMG00000019243

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