Name : ADAMTS8 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN2962498984
| Long name | Cy3 Conjugated, ADAMTS8 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ADAMTS8 |
| Specificity | This is a highly specific antibody against ADAMTS8 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human ADAMTS8 |
| Gene ID number | 11095 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | 2, 3 and 4, ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, ADAMTS8 has a propeptide domain, ADAMTS8 is inhibited by the endogenous MMP inhibitors, In addition to the metalloprotease domain, TIMP1, The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, They have been demonstrated to have important roles in connective tissue organization, a Prohormone Convertase (PC, a cysteine rich domain and thrombospondin 1 like domains, and has been shown to be proteolytically active on a range of substrates, angiogenesis and cell migration, arthritis, but most efficiently by TIMP3, coagulation, furin) cleavage site, inflammation, the function of ADAMTS8 is still poorly understood, versican and brevican, A member of the metalloproteinase family containing disintegrin like domains (ADAMs), ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | METH2 FLJ41712 ADAM-TS8 |
| Properties | 1 of the ADAMTS8 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ADAMTS8 Conjugated |
| Short name | Conjugated, ADAMTS8 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | 8 (Antibody to), cyanine 3 coupled, ADAM metallopeptidase including thrombospondin classification 1 motif |
| Alternative technique | antibodies |
| Alternative to gene target | 8, ADAM-TS8 and METH2, ADAMTS8 and IDBG-642991 and ENSBTAG00000010411 and 512544, ADAMTS8 and IDBG-76259 and ENSG00000134917 and 11095, Adamts8 and IDBG-146397 and ENSMUSG00000031994 and 30806, Extracellular, low affinity phosphate transmembrane transporter activity, this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0006508 and proteolysis and biological process this GO :0008201 and heparin binding and molecular function this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009673 and low affinity phosphate transmembrane transporter activity and molecular function this GO :0031012 and extracellular matrix and cellular component this GO :0035435 and phosphate ion transmembrane transport and biological process, this GO :0004222: metalloendopeptidase activity, this GO :0004222: metalloendopeptidase activity and also this GO :0005178: integrin binding and also this GO :0008201: heparin binding and also this GO :0008237: metallopeptidase activity and also this GO :0008270: zinc ion binding and also this GO :0009673: low affinity phosphate transmembrane transporter activity, this GO :0005178: integrin binding, this GO :0008201: heparin binding, this GO :0008237: metallopeptidase activity, this GO :0008270: zinc ion binding, this GO :0009673: low affinity phosphate transmembrane transporter activity, ADAM metallopeptidase with thrombospondin type 1 motif |
| Identity | 224 |
| Gene | ADAMTS8 |
| Long gene name | ADAM metallopeptidase with thrombospondin type 1 motif 8 |
| Synonyms gene name | 8 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif |
| Locus | 11q24, 3 |
| Discovery year | 1999-08-23 |
| GenBank acession | AF060153 |
| Entrez gene record | 11095 |
| Pubmed identfication | 10438512 |
| RefSeq identity | NM_007037 |
| Classification | ADAM metallopeptidases with thrombospondin type 1 motif |
| Havana BLAST/BLAT | OTTHUMG00000165656 |