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Adeno-Associated Virus Capsid Protein VP1 Antibody, Biotin Conjugated

Adeno-Associated Virus Capsid Protein VP1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Adeno-Associated Virus Capsid Protein VP1 Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAdeno-Associated Virus Capsid Protein VP1
Specificity AAV3B, AAV4, AAV9, This antibody will recognize many AAV strains, and AAV13, including AAV5, This is a highly specific antibody against Adeno-Associated Virus Capsid Protein VP1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range30-80/724
SourceKLH conjugated synthetic peptide derived from Adeno-Associated Virus 5 capsid protein VP1
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityVirus
Crossreactive species detailsAAV5
Antigen background Binding to the host receptor also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, Binds to host cell heparan sulfate and uses host ITGA5-ITGB1 as coreceptor on the cell surface to provide virion attachment to target cell, The capsid encapsulates the genomic ssDNA, This attachment induces virion internalization predominantly through clathrin-dependent endocytosis, VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus, VP2 and VP3 which differ in their N-terminus, about 22 nm in diameter, and consisting of 60 copies of three size variants of the capsid protein VP1, specifically its phospholipase A2-like region and putative nuclear localization signal(s), Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Parvovirus coat protein VP1, capsid protein, capsid protein AAV5, capsid protein [Adeno-associated virus - 5], capsid protein Adeno-associated 5 virus
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAdeno-Associated Virus Capsid Protein VP1 Conjugated
Short name Conjugated, Adeno-Associated Virus Capsid Protein VP1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Species Viruses, Virus
Alternative name biotinilated coupled, Adeno-Associated Virus Capsid Protein VP1 (Antibody to)
Alternative techniqueantibodies

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