Name : Adeno-Associated Virus Capsid Protein VP1 Antibody, Cy5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN4915592740
| Long name | Cy5 Conjugated, Adeno-Associated Virus Capsid Protein VP1 Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Adeno-Associated Virus Capsid Protein VP1 |
| Specificity | AAV3B, AAV4, AAV9, This antibody will recognize many AAV strains, and AAV13, including AAV5, This is a highly specific antibody against Adeno-Associated Virus Capsid Protein VP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 30-80/724 |
| Source | KLH conjugated synthetic peptide derived from Adeno-Associated Virus 5 capsid protein VP1 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Virus |
| Crossreactive species details | AAV5 |
| Antigen background | Binding to the host receptor also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, Binds to host cell heparan sulfate and uses host ITGA5-ITGB1 as coreceptor on the cell surface to provide virion attachment to target cell, The capsid encapsulates the genomic ssDNA, This attachment induces virion internalization predominantly through clathrin-dependent endocytosis, VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus, VP2 and VP3 which differ in their N-terminus, about 22 nm in diameter, and consisting of 60 copies of three size variants of the capsid protein VP1, specifically its phospholipase A2-like region and putative nuclear localization signal(s), Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 625, 650nm/670nm |
| Synonyms | Parvovirus coat protein VP1, capsid protein, capsid protein AAV5, capsid protein [Adeno-associated virus - 5], capsid protein Adeno-associated 5 virus |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Adeno-Associated Virus Capsid Protein VP1 Conjugated |
| Short name | Conjugated, Adeno-Associated Virus Capsid Protein VP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy5 |
| Species | Viruses, Virus |
| Alternative name | cyanine 5 coupled, Adeno-Associated Virus Capsid Protein VP1 (Antibody to) |
| Alternative technique | antibodies |