| Long name | ADRB1 Primary Polyclonal Antibody |
| Also known as | ADRB1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ADRB1 |
| Specificity | This is a highly specific antibody against ADRB1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 197-222/477 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADRB1 |
| Gene ID number | 153 |
| Swiss Prot | P08588 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling, This receptor binds epinephrine and norepinephrine with approximately equal affinity, Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ADRB1, ADRB1R, B1AR, BETA1AR, Beta-1 adrenergic receptor, Beta-1 adrenoceptor, Beta-1 adrenoreceptor, RHR |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ADRB1 |
| Short name | ADRB1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | adrenoceptor b 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | ADRB1 and IDBG-90231 and ENSG00000043591 and 153, ADRB1R and B1AR and BETA1AR and RHR, Adrb1 and IDBG-179107 and ENSMUSG00000035283 and 11554, BT, norepinephrine binding, nuclei, this GO :0001996 and positive regulation of heart rate by epinephrine-norepinephrine and biological process this GO :0001997 and positive regulation of the force of heart contraction by epinephrine-norepinephrine and biological process this GO :0002024 and diet induced thermogenesis and biological process this GO :0002025 and vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure and biological process this GO :0003061 and positive regulation of the force of heart contraction by norepinephrine and biological process this GO :0003084 and positive regulation of systemic arterial blood pressure and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004939 and beta-adrenergic receptor activity and molecular function this GO :0004940 and beta1-adrenergic receptor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005088 and Ras guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005769 and early endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005980 and glycogen catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007189 and adenylate cyclase-activating G-protein coupled receptor signaling pathway and biological process this GO :0007190 and activation of adenylate cyclase activity and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0007568 and aging and biological process this GO :0007613 and memory and biological process this GO :0008144 and drug binding and molecular function this GO :0009409 and response to cold and biological process this GO :0010460 and positive regulation of heart rate and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019233 and sensory perception of pain and biological process this GO :0030165 and PDZ domain binding and molecular function this GO :0030819 and positive regulation of cAMP biosynthetic process and biological process this GO :0031649 and heat generation and biological process this GO :0031694 and alpha-2A adrenergic receptor binding and molecular function this GO :0032320 and positive regulation of Ras GTPase activity and biological process this GO :0033365 and protein localization to organelle and biological process this GO :0035240 and dopamine binding and molecular function this GO :0035811 and negative regulation of urine volume and biological process this GO :0040015 and negative regulation of multicellular organism growth and biological process this GO :0042060 and wound healing and biological process this GO :0042596 and fear response and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043950 and positive regulation of cAMP-mediated signaling and biological process this GO :0045986 and negative regulation of smooth muscle contraction and biological process this GO :0046878 and positive regulation of saliva secretion and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050873 and brown fat cell differentiation and biological process this GO :0051379 and epinephrine binding and molecular function this GO :0051380 and norepinephrine binding and molecular function this GO :0051924 and regulation of calcium ion transport and biological process this GO :0055088 and lipid homeostasis and biological process this GO :0060080 and regulation of inhibitory postsynaptic membrane potential and biological process this GO :0061051 and positive regulation of cell growth involved in cardiac muscle cell development and biological process this GO :0071880 and adenylate cyclase-activating adrenergic receptor signaling pathway and biological process this GO :0086004 and regulation of cardiac muscle cell contraction and biological process this GO :1900135 and positive regulation of renin secretion into blood stream and biological process this GO :2001259 and positive regulation of cation channel activity and biological process, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0004939: beta-adrenergic receptor activity and also this GO :0004940: beta1-adrenergic receptor activity and also this GO :0005057: receptor signaling protein activity and also this GO :0005088: Ras guanyl-nucleotide exchange factor activity and also this GO :0005515: protein binding and also this GO :0008144: drug binding and also this GO :0030165: PDZ domain binding and also this GO :0031694: alpha-2A adrenergic receptor binding and also this GO :0035240: dopamine binding and also this GO :0046982: protein heterodimerization activity and also this GO :0051379: epinephrine binding and also this GO :0051380: norepinephrine binding, this GO :0004939: beta-adrenergic receptor activity, this GO :0004940: beta1-adrenergic receptor activity, this GO :0005057: receptor signaling protein activity, this GO :0005088: Ras guanyl-nucleotide exchange factor activity, this GO :0005515: protein binding, this GO :0008144: drug binding, this GO :0030165: PDZ domain binding, this GO :0031694: alpha-2A adrenergic receptor binding, this GO :0035240: dopamine binding, this GO :0046982: protein heterodimerization activity, this GO :0051379: epinephrine binding, this GO :0051380: norepinephrine binding, 79981 and IDBG-648826 and ENSBTAG00000001242 and 281604, adrenoceptor beta 1 |
| Identity | 285 |
| Gene | ADRB1 |
| Long gene name | adrenoceptor beta 1 |
| Synonyms gene | ADRB1R |
| Synonyms gene name | adrenergic, beta-1-, receptor |
| Locus | 10q25, 3 |
| Discovery year | 1990-09-10 |
| GenBank acession | J03019 |
| Entrez gene record | 153 |
| Classification | Adrenoceptors |
| Havana BLAST/BLAT | OTTHUMG00000019079 |
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