Name : AF 4 protein Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4784859657
| Long name | ALEXA FLUOR 594 Conjugated, AF 4 protein Polyclonal Antibody |
| Also known as | Anti-AF 4 protein PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | AF 4 protein |
| Specificity | This is a highly specific antibody against AF 4 protein |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AF 4 protein |
| Gene ID Number | 4299 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | MLL is involved in several chromosomal translocations associated with acute myeloid and lymphoid leukemia, The MLL-AF-4 fusion protein is expressed in all normal hematopoietic cells, The expression of MLL-AF-4 influences the production of protein cyclin-dependent kinase inhibitor (CDKN1B), The fusion of AF-4 on chromosome band 4q21 with the mixed lineage leukemia (MLL or HRX) gene on 11q23 results in a MLL-AF-4 chimeric transcription factor in which AF-4 contributes transcriptional effector properties and requires cell-specific accessory factors, suggesting that inhibition of MLL-AF-4 expression may be a powerful and highly specific treatment of chemotherapy-resistant leukemia, which is associated with acute leukemias, Proto-oncogene AF-4 (or FEL) is a product of a chromosomal aberration of the human gene AFF1 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | AF 4 protein, AF-4 protein, AF4/FMR2 family member 1, AFF 1, AFF1, AFF1_HUMAN, ALL1 fused gene from chromosome 4, ALL1-fused gene from chromosome 4 protein, FEL, MLLT2, MLLT2, MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA TRANSLOCATED TO 2, Protein AF-4, Protein FEL, Proto-oncogene AF4, AF 4 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | AF 4 protein |
| Short name | AF 4 protein Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, AF 4 protein (Antibody to) |
| Alternative technique | antibodies |