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AFAP1L2 Antibody

AFAP1L2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAFAP1L2 Primary Polyclonal Antibody
Also known asAFAP1L2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAFAP1L2
SpecificityThis is a highly specific antibody against AFAP1L2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AFAP1L2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen AFAP-110 contains additional protein-binding domains as well, AFAP-110 provides a platform for the preparation of larger signaling complexes, AFAP-1L2 (Actin filament-associated protein 1-like 2), AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation, AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, By linking signaling molecules to actin filaments, Like its relative AFAP110, There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein, also known as XB130, and serves as an adaptor protein, brain, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, pancreas and kidney, which are normally found in proteins involved in intracellular signaling, Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AF1L2_HUMAN, AFAP1-like protein 2, Actin filament-associated protein 1-like 2, XB130, afap1l2, KIAA1914
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAFAP1L2
Short nameAFAP1L2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameactin filament associated protein 1-like 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target AFAP1L2 and IDBG-640002 and ENSBTAG00000004895 and 615436, AFAP1L2 and IDBG-90372 and ENSG00000169129 and 84632, Afap1l2 and IDBG-179434 and ENSMUSG00000025083 and 226250, Cytoplasm, DNA-templated and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process, SH2 domain binding, this GO :0005737 and cytoplasm and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007346 and regulation of mitotic cell cycle and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0030296 and protein tyrosine kinase activator activity and molecular function this GO :0032675 and regulation of interleukin-6 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0045742 and positive regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0045893 and positive regulation of transcription, this GO :0017124: SH3 domain binding, this GO :0017124: SH3 domain binding and also this GO :0030296: protein tyrosine kinase activator activity and also this GO :0042169: SH2 domain binding, this GO :0030296: protein tyrosine kinase activator activity, this GO :0042169: SH2 domain binding, actin filament associated protein 1-like 2
Identity 25901
Gene AFAP1L2
Long gene name actin filament associated protein 1 like 2
Synonyms gene KIAA1914
Synonyms gene name KIAA1914 actin filament associated protein 1-like 2
Synonyms FLJ14564 Em:AC005383, 4 XB130
Locus 10q25, 3
Discovery year 2004-02-18
GenBank acession BC024314
Entrez gene record 84632
Pubmed identfication 11572484 17412687
RefSeq identity NM_032550
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000019086

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