Name : AFG3L2 Antibody
Supplier : NJS POLY
Price :406
SKU : GEN8303935751
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | AFG3L2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 1-0, 5ug/ml, Western blot: 0 |
| Notes | Optimal dilution of the AFG3L2 antibody should be determined by the researcher |
| Intented use | This AFG3L2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9Y4W6 |
| Purity | Antigen affinity |
| Description | And this gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome, In humans, The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia, This gene encodes a protein localized in mitochondria and closely related to paraplegin, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly, it is encoded by the AFG3L2 gene, AFG3L2 is the catalytic subunit of the m-AAA protease |
| Immunogen | Amino acids R168-D250 of the human protein were used as the immunogen for the AFG3L2 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the AFG3L2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | AFG3L2 |
| Short name | AFG3L2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | AFG3L2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 315 |
| Gene | AFG3L2 |
| Long gene name | AFG3 like matrix AAA peptidase subunit 2 |
| Synonyms gene | SCA28 |
| Synonyms gene name | AFG3 (ATPase family gene 3, cerevisiae) AFG3 like AAA ATPase 2 , yeast)-like 2 spinocerebellar ataxia 28 AFG3 ATPase family member 3-like 2 (S |
| Synonyms | SPAX5 |
| Locus | 18p11, 21 |
| Discovery year | 1999-07-13 |
| GenBank acession | Y18314 |
| Entrez gene record | 10939 |
| Pubmed identfication | 10395799 18769991 |
| RefSeq identity | NM_006796 |
| Classification | AAA ATPases |
| Havana BLAST/BLAT | OTTHUMG00000131695 |
| Locus Specific Databases | LRG_666 |