Name : Aggrecan Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5057224751
| Long name | ALEXA FLUOR 488 Conjugated, Aggrecan Polyclonal Antibody |
| Also known as | Anti-Aggrecan PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Aggrecan |
| Specificity | This is a highly specific antibody against Aggrecan |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 180-230/2415 |
| Subcellular location | Secreted |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Aggrecan |
| Swiss Prot | P16112 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Aggrecan accounts for the compressive stiffness and resilience of the hyaline cartilage, Aggrecan in cartilage forms aggregates with hyaluronan and link protein, Aggrecan is a complex multidomain macromolecule that undergoes extensive processing and post-translational modification, Aggrecan is a member of the chondroitin sulphate proteoglycan family, Brevican is a brain proteoglycan of the aggrecan/versican/neurocan family, In the adult brain, Many forms of inflammatory arthritis are shown to be accompanied with aggrecan degradation and loss from the cartilage, aggrecan, embedded in a collagen network, is the predominant proteoglycan present in cartilage, neurocan and brevican, the brevican core protein undergoes proteolytic cleavage and exists as a full-length form a carboxy-terminal fragment and an amino-terminal fragment, which also includes versican/PG-M, The large chondroitin sulfate proteoglycan |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | CSPGCP ACAN |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Aggrecan Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Aggrecan |
| Short name | Aggrecan Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Aggrecan (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7338 |
| Gene | MSK16 |
| Long gene name | aggrecan |
| Synonyms gene | CSPG1 AGC1 |
| Synonyms gene name | chondroitin sulfate proteoglycan 1 aggrecan 1 |
| Synonyms name | aggrecan proteoglycan |
| Locus | 15q26, 1 |
| Discovery year | 1992-06-17 |
| GenBank acession | M55172 |
| Entrez gene record | 176 |
| Pubmed identfication | 1985970 |
| RefSeq identity | NM_001135 |
| Classification | Sushi domain containing Hyalectan proteoglycans V-set domain containing C-type lectin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000171989 |