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Agrin Antibody

Agrin Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAgrin Primary Polyclonal Antibody
Also known asAgrin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAgrin
SpecificityThis is a highly specific antibody against Agrin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from mouse Agrin
Gene ID number375790
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Rat, Mouse
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Agrin, Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction, MuSK and Rapsyn are all essential components for AChR aggregation, The C-terminal region of agrin is released into the medium, The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components, The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin, This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites, increasing the predicted MW from 200kDa to ~600kDa, interacts with receptors on the muscle surface and induces AChR aggregation, through an unknown mechanism, Agrin is a neuronal aggregating factor that induces the aggregation of acetylcholine receptors and other postsynaptic proteins on muscle fibers and is crucial for the formation of the neuromuscular junction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AGRIN_HUMAN, AGRIN_MOUSE, AGRN, Agrin proteoglycan, FLJ45064, OTTHUMP00000044043, AGRIN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAgrin
Short nameAgrin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAgrin (Antibody to)
Alternative techniqueantibodies
Identity 329
Gene AGRN
Long gene name agrin
Synonyms AGRIN
Synonyms name agrin proteoglycan
Locus 1p36, 33
Discovery year 1992-02-14
GenBank acession XM_372195
Entrez gene record 375790
Pubmed identfication 1851019 12270958
RefSeq identity NM_198576
Classification Proteoglycans
Havana BLAST/BLAT OTTHUMG00000040778
Locus Specific Databases Leiden Muscular Dystrophy pages LRG_198

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