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Agrin Antibody, ALEXA FLUOR 488

Agrin Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Agrin Polyclonal Antibody
Also known asAnti-Agrin PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAgrin
SpecificityThis is a highly specific antibody against Agrin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from mouse Agrin
Gene ID Number375790
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Rat, Mouse
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Agrin, Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction, MuSK and Rapsyn are all essential components for AChR aggregation, The C-terminal region of agrin is released into the medium, The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components, The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin, This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites, increasing the predicted MW from 200kDa to ~600kDa, interacts with receptors on the muscle surface and induces AChR aggregation, through an unknown mechanism, Agrin is a neuronal aggregating factor that induces the aggregation of acetylcholine receptors and other postsynaptic proteins on muscle fibers and is crucial for the formation of the neuromuscular junction
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms AGRIN
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Agrin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetAgrin
Short nameAgrin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Agrin (Antibody to)
Alternative techniqueantibodies
Identity 329
Gene AGRN
Long gene name agrin
Synonyms name agrin proteoglycan
Locus 1p36, 33
Discovery year 1992-02-14
GenBank acession XM_372195
Entrez gene record 375790
Pubmed identfication 1851019 12270958
RefSeq identity NM_198576
Classification Proteoglycans
Havana BLAST/BLAT OTTHUMG00000040778
Locus Specific Databases Leiden Muscular Dystrophy pages LRG_198

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