Filters

Agrin Antibody, Biotin Conjugated

Agrin Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Agrin Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAgrin
SpecificityThis is a highly specific antibody against Agrin
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from mouse Agrin
Gene ID number375790
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Rat, Mouse
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Agrin, Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction, MuSK and Rapsyn are all essential components for AChR aggregation, The C-terminal region of agrin is released into the medium, The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components, The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin, This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites, increasing the predicted MW from 200kDa to ~600kDa, interacts with receptors on the muscle surface and induces AChR aggregation, through an unknown mechanism, Agrin is a neuronal aggregating factor that induces the aggregation of acetylcholine receptors and other postsynaptic proteins on muscle fibers and is crucial for the formation of the neuromuscular junction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms AGRIN_HUMAN, AGRIN_MOUSE, AGRN, Agrin proteoglycan, FLJ45064, OTTHUMP00000044043, AGRIN
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAgrin Conjugated
Short name Conjugated, Agrin Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Agrin (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter