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AICDA Antibody

AICDA Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAICDA Primary Polyclonal Antibody
Also known asAICDA PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAICDA
SpecificityThis is a highly specific antibody against AICDA
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range140-190/198
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AICDA
Gene ID number57379
Swiss ProtQ9GZX7
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Involved in somatic hypermutation, May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation, Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses, and class-switch recombination in B-lymphocytes, gene conversion, Single-stranded DNA-specific cytidine deaminase
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AICDA, ARP2, Activation-induced cytidine deaminase, CDA2, Cytidine aminohydrolase, HEL-S-284, HIGM2, Single-stranded DNA cytosine deaminase, AID
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAICDA
Short nameAICDA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameactivation-induced cytidine deaminase (Antibody to)
Alternative techniqueantibodies
Alternative to gene target AICDA and IDBG-17253 and ENSG00000111732 and 57379, Aicda and IDBG-185563 and ENSMUSG00000040627 and 11628, BT, acting on carbon-nitrogen (but not peptide) bonds, acting on carbon-nitrogen (but not peptide) bonds, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, in cyclic amidines, in cyclic amidines, in cyclic amidines and molecular function this GO :0030183 and B cell differentiation and biological process this GO :0045087 and innate immune response and biological process this GO :0045190 and isotype switching and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0080111 and DNA demethylation and biological process this GO :0090310 and negative regulation of methylation-dependent chromatin silencing and biological process, nuclei, this GO :0000178 and exosome (RNase complex) and cellular component this GO :0003824 and catalytic activity and molecular function this GO :0004126 and cytidine deaminase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006397 and mRNA processing and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009972 and cytidine deamination and biological process this GO :0016445 and somatic diversification of immunoglobulins and biological process this GO :0016446 and somatic hypermutation of immunoglobulin genes and biological process this GO :0016814 and hydrolase activity, this GO :0003824: catalytic activity, this GO :0003824: catalytic activity and also this GO :0004126: cytidine deaminase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016814: hydrolase activity, this GO :0004126: cytidine deaminase activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016814: hydrolase activity, 56893 and IDBG-639763 and ENSBTAG00000018849 and 539888, activation-induced cytidine deaminase
Identity 13203
Gene AICDA
Long gene name activation induced cytidine deaminase
Synonyms gene name activation-induced cytidine deaminase
Synonyms HIGM2 CDA2 ARP2 AID
Locus 12p13, 31
Discovery year 2000-09-19
GenBank acession AB040430
Entrez gene record 57379
RefSeq identity NM_020661
Classification Apolipoprotein B mRNA editing enzyme catalytic subunits
Havana BLAST/BLAT OTTHUMG00000168676
Locus Specific Databases AICDA base: Mutation registry for Aid deficiency LRG_17

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