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AIF Antibody, Cy5 Conjugated

AIF Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, AIF Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAIF
SpecificityThis is a highly specific antibody against AIF
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range130-180/613
Subcellular location Mitochondrion, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human AIF
Gene ID number9131
Swiss ProtO95831
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Pig, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binds to DNA in a sequence-independent manner, In contrast, In response to apoptotic stimuli, Interacts with EIF3G, Plays a critical role in caspase-independent, The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i, and activates casapse-7 to amplify apoptosis, caspase-independent fragmentation of chromosomal DNA, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, pyknotic cell death in hydrogen peroxide-exposed cells, where it functions as a proapoptotic factor in a caspase-independent pathway, Functions both as NADH oxidoreductase and as regulator of apoptosis, and thereby inhibits the EIF3 machinery and protein synthesis, e
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms AIF CMTX4
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAIF Conjugated
Short name Conjugated, AIF Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, AIF (Antibody to)
Alternative techniqueantibodies
Identity 8768
Gene AIFM1
Long gene name apoptosis inducing factor mitochondria associated 1
Synonyms gene PDCD8 NAMSD
Synonyms gene name 1 apoptosis inducing factor, axonal, mitochondria associated 1 , mitochondrion-associated, motor-sensory with deafness and mental retardation (Cowchock syndrome) apoptosis-inducing factor, programmed cell death 8 (apoptosis-inducing factor) neuropathy
Locus Xq26, 1
Discovery year 1999-05-28
GenBank acession AF100928
Entrez gene record 9131
Pubmed identfication 9989411 23217327
Havana BLAST/BLAT OTTHUMG00000022392
Locus Specific Databases Mental Retardation database

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