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AIF Antibody, FITC Conjugated

AIF Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, AIF Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAIF
SpecificityThis is a highly specific antibody against AIF
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range130-180/613
Subcellular location Mitochondrion, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human AIF
Gene ID number9131
Swiss ProtO95831
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Pig, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binds to DNA in a sequence-independent manner, In contrast, In response to apoptotic stimuli, Interacts with EIF3G, Plays a critical role in caspase-independent, The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i, and activates casapse-7 to amplify apoptosis, caspase-independent fragmentation of chromosomal DNA, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, pyknotic cell death in hydrogen peroxide-exposed cells, where it functions as a proapoptotic factor in a caspase-independent pathway, Functions both as NADH oxidoreductase and as regulator of apoptosis, and thereby inhibits the EIF3 machinery and protein synthesis, e
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms AIF CMTX4
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAIF Conjugated
Short name FITC Conjugated, AIF Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, AIF (Antibody to)
Alternative techniqueantibodies
Identity 8768
Gene AIFM1
Long gene name apoptosis inducing factor mitochondria associated 1
Synonyms gene PDCD8 NAMSD
Synonyms gene name 1 apoptosis inducing factor, axonal, mitochondria associated 1 , mitochondrion-associated, motor-sensory with deafness and mental retardation (Cowchock syndrome) apoptosis-inducing factor, programmed cell death 8 (apoptosis-inducing factor) neuropathy
Locus Xq26, 1
Discovery year 1999-05-28
GenBank acession AF100928
Entrez gene record 9131
Pubmed identfication 9989411 23217327
Havana BLAST/BLAT OTTHUMG00000022392
Locus Specific Databases Mental Retardation database

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