| Long name | AIF1 Primary Polyclonal Antibody |
| Also known as | AIF1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | AIF1 |
| Specificity | This is a highly specific antibody against AIF1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 116-147/147 |
| Subcellular location | Membrane bound, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AIF1 |
| Gene ID number | 199 |
| Swiss Prot | P55008 |
| Tested Applications | IF(IHC-F), IF(IHC-P), IHC-F, IHC-P, WB |
| Recommended dilutions | IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200), IHC-F(1:100-500), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds calcium, Enhances lymphocyte migration, Enhances the actin-bundling activity of LCP1, May play a role in macrophage activation and function, Plays a role in RAC signaling and in phagocytosis, Plays a role in vascular inflammation, Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes, Actin-binding protein that enhances membrane ruffling and RAC activation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AIF-1, AIF1, Allograft inflammatory factor 1, G1, IRT-1, IRT1, Ionized calcium-binding adapter molecule 1, Protein G1, IBA1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | AIF1 |
| Short name | AIF1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | allograft inflammatory factor 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | AIF-1 and IBA1 and IRT-1 and IRT1, AIF1 and IDBG-634144 and ENSBTAG00000020554 and 280989, AIF1 and IDBG-78190 and ENSG00000204472 and 199, Aif1 and IDBG-177226 and ENSMUSG00000024397 and 11629, actin filament binding, engulfment and biological process this GO :0006954 and inflammatory response and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0014739 and positive regulation of muscle hyperplasia and biological process this GO :0016601 and Rac protein signal transduction and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030041 and actin filament polymerization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031668 and cellular response to extracellular stimulus and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0034097 and response to cytokine and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042995 and cell projection and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043204 and perikaryon and cellular component this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0048678 and response to axon injury and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051017 and actin filament bundle assembly and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0071315 and cellular response to morphine and biological process this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0071447 and cellular response to hydroperoxide and biological process this GO :0071672 and negative regulation of smooth muscle cell chemotaxis and biological process this GO :0071673 and positive regulation of smooth muscle cell chemotaxis and biological process this GO :0090026 and positive regulation of monocyte chemotaxis and biological process this GO :0097178 and ruffle assembly and biological process this GO :1900087 and positive regulation of G1/S transition of mitotic cell cycle and biological process this GO :2000406 and positive regulation of T cell migration and biological process, nuclei, this GO :0001726 and ruffle and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0001891 and pha this GO cytic cup and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003674 and molecular function and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005884 and actin filament and cellular component this GO :0006911 and pha this GO cytosis, this GO :0003674: molecular_function, this GO :0003674: molecular_function and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0051015: actin filament binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0051015: actin filament binding, allograft inflammatory factor 1 |
| Identity | 352 |
| Gene | AIF1 |
| Long gene name | allograft inflammatory factor 1 |
| Synonyms | IRT-1 AIF-1 Em:AF129756, 17 IBA1 |
| Synonyms name | interferon gamma responsive transcript ionized calcium-binding adapter molecule 1 |
| Locus | 6p21, 33 |
| Discovery year | 1997-07-01 |
| GenBank acession | U19713 |
| Entrez gene record | 199 |
| Pubmed identfication | 8912632 |
| Classification | EF-hand domain containing |
| Havana BLAST/BLAT | OTTHUMG00000031246 |
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