| Long name | AIP1 Primary Polyclonal Antibody |
| Also known as | AIP1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | AIP1 |
| Specificity | This is a highly specific antibody against AIP1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AIP1 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukemia (AML), Expressed at low levels in prostate tissue, also known as DAB2IP (DAB2 interacting protein), disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, implicating a role for AIP1 fusion proteins in tumorigenesis, is a 1, one PH domain and one C2 domain, suggesting a role in tumor suppression, thereby allowing free ASK 1 to function within the cell, via this interaction, 189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, AIP1 (ASK-interacting protein 1) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ACVRIP1, AIP 1, ARIP1, Acvri1, Acvrinp1, Aip-1, Atrophin 1 interacting protein 1, Atrophin 1 interacting protein A, Atrophin-1-interacting protein 1, Atrophin-1-interacting protein A, MAGI-2, MAGI2, MAGI2_HUMAN, Membrane associated guanylate kinase 2, Membrane associated guanylate kinase WW and PDZ domain containing 2, Membrane associated guanylate kinase WW and PDZ domain containing protein 2, Membrane associated guanylate kinase inverted 2, Membrane-associated guanylate kinase, Membrane-associated guanylate kinase inverted 2, S SCAM, SSCAM, WW and PDZ domain-containing protein 2, Activin receptor interacting protein 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | AIP1 |
| Short name | AIP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | AIP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 8766 |
| Gene | PDCD6IP |
| Long gene name | programmed cell death 6 interacting protein |
| Synonyms gene name | programmed cell death 6-interacting protein |
| Synonyms | Alix AIP1 Hp95 |
| Synonyms name | ALG-2 interacting protein X |
| Locus | 3p22, 3 |
| Discovery year | 1999-12-10 |
| GenBank acession | BC020066 |
| Entrez gene record | 10015 |
| Pubmed identfication | 9880530 |
| Havana BLAST/BLAT | OTTHUMG00000130751 |
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