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AKT3 Antibody

AKT3 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAKT3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Primate, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB, IHC
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the AKT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis AKT3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9Y243
PurityPurified
Description AKT2 and AKT3) called the AKT kinase, AKT3 is the least studied AKT isoform, AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13, Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, It plays an important role in brain development and is crucial for the viability of malignant glioma cells, Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands, [UniProt], and which regulate many processes including metabolism, cell survival, growth and angiogenesis, proliferation, resulting in the induction of caspase-dependent apoptosis, AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1
ImmunogenA portion of amino acids 88-118 from the human protein was used as the immunogen for this AKT3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AKT3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetAKT3
Short nameAKT3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAKT3 (Antibody to)
Alternative techniqueantibodies
Identity 393
Gene AKT3
Long gene name AKT serine/threonine kinase 3
Synonyms gene name v-akt murine thymoma viral oncogene homolog 3
Synonyms PKBG RAC-gamma PRKBG
Synonyms name gamma , protein kinase B
Locus 1q43-q44
Discovery year 1999-11-16
GenBank acession AF124141
Entrez gene record 10000
Pubmed identfication 10092583 10208883
RefSeq identity NM_181690
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000039994

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