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ALAS1 Antibody, ALEXA FLUOR 488

ALAS1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, ALAS1 Polyclonal Antibody
Also known asAnti-ALAS1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenALAS1
SpecificityThis is a highly specific antibody against ALAS1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ALAS1/ALAS-H
Gene ID Number211
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen ALAS-E, ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells, NF-E2 and EKLF, Since the ALAS gene maps to the X chromosome, Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H, The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, The erythroid-specific isoenzyme, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver, 5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ALAS1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetALAS1
Short nameALAS1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, ALAS1 (Antibody to)
Alternative techniqueantibodies
Identity 396
Gene ALAS1
Long gene name 5', -aminolevulinate synthase 1
Synonyms gene ALAS3 ALAS
Synonyms gene name aminolevulinate, delta-, synthase 1
Locus 3p21, 2
Discovery year 1986-01-01
GenBank acession X56351
Entrez gene record 211
Havana BLAST/BLAT OTTHUMG00000158108

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