Name : ALDH2 (138CT22.3.8) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN2657370585
| Long name | 3, 8) Monoclonal Antibody, ALDH2 (138CT22 |
| Also known as | 3, 8) Monoclonal Antibody, ALDH2 (138CT22 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ALDH2 |
| Specificity | This is a highly specific antibody against ALDH2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 138CT22, 3, 8 |
| Source | This ALDH2 Monoclonal antibody is generated from mouse immunized with ALDH2 recombinant protein |
| Gene ID number | 217 |
| Swiss Prot | P05091 |
| Tested Applications | FCM, IF, IHC-P, WB |
| Recommended dilutions | FC(1:10-50), IHC-P(1:50-100), WB(1:1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme, Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism, Most Caucasians have two major isozymes, This gene encodes a mitochondrial isoform, Two major liver isoforms of this enzyme, and is localized in mitochondrial matrix, and subcellular localizations, can be distinguished by their electrophoretic mobilities, cytosolic and mitochondrial, kinetic properties, missing the mitochondrial isozyme, which has a low Km for acetaldehydes, while approximately 50% of Orientals have only the cytosolic isozyme, This protein belongs to the aldehyde dehydrogenase family of proteins |
| Purification method | This antibody is purified through a protein G column, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ALDH class 2, ALDH-E2, ALDH2, ALDHI, Aldehyde dehydrogenase, mitochondrial, ALDM |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 3, 8) Monoclonal, ALDH2 (138CT22 |
| Short name | 3, 8) Monoclonal Antibody, ALDH2 (138CT22 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 3, 8) monoclonal (Antibody to), aldehyde dehydrogenase 2 family (mitochondrial) (138CT22 |
| Alternative technique | antibodies |
| Alternative to gene target | ALDH-E2 and ALDHI and ALDM, ALDH2 and IDBG-57710 and ENSG00000111275 and 217, multiple, oxidoreductase activity, this GO :0004029 and aldehyde dehydrogenase (NAD) activity and molecular function this GO :0004030 and aldehyde dehydrogenase [NAD(P)+] activity and molecular function this GO :0005759 and mitochondrial matrix and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006066 and alcohol metabolic process and biological process this GO :0006068 and ethanol catabolic process and biological process this GO :0006069 and ethanol oxidation and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0007268 and synaptic transmission and biological process this GO :0008152 and metabolic process and biological process this GO :0009055 and electron carrier activity and molecular function this GO :0016491 and oxidoreductase activity and molecular function this GO :0042136 and neurotransmitter biosynthetic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004029: aldehyde dehydrogenase (NAD) activity, this GO :0004029: aldehyde dehydrogenase (NAD) activity and also this GO :0004030: aldehyde dehydrogenase [NAD(P)+] activity and also this GO :0009055: electron carrier activity and also this GO :0016491: oxidoreductase activity, this GO :0004030: aldehyde dehydrogenase [NAD(P)+] activity, this GO :0009055: electron carrier activity, this GO :0016491: oxidoreductase activity, aldehyde dehydrogenase 2 family (mitochondrial) |
| Identity | 404 |
| Gene | ALDH2 |
| Long gene name | aldehyde dehydrogenase 2 family (mitochondrial) |
| Locus | 12q24, 12 |
| Discovery year | 1986-01-01 |
| GenBank acession | M26760 |
| Entrez gene record | 217 |
| Pubmed identfication | 4015823 2987944 |
| RefSeq identity | NM_000690 |
| Classification | Aldehyde dehydrogenases |
| Havana BLAST/BLAT | OTTHUMG00000169603 |
| Locus Specific Databases | Human Polymorphisms of ALDH Genes |