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ALIX Antibody

ALIX Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenALIX
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions1-0, 5ug/ml, Western blot: 0
NotesOptimal dilution of the ALIX antibody should be determined by the researcher
Intented useThis ALIX antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q8WUM4
PurityAntigen affinity
Description In addition, Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, Studies using mouse cells have shown that overexpression of this protein can block apoptosis, This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, This gene product also binds to endophilins, a protein required for apoptosis, and in enveloped virus budding, in a calcium-dependent manner, in intralumenal endosomal vesicle formation, is a protein that in humans is encoded by the PDCD6IP gene, or ALG-2-interacting protein X, proteins that regulate membrane shape during endocytosis, the product of this gene binds to the product of the PDCD6 gene, which may be partly responsible for the protection against cell death, Programmed cell death 6-interacting protein
ImmunogenAmino acids 2-330 of human ALIX were used as the immunogen for the ALIX antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ALIX antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetALIX
Short nameALIX Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameALIX (Antibody to)
Alternative techniqueantibodies
Identity 8766
Gene PDCD6IP
Long gene name programmed cell death 6 interacting protein
Synonyms gene name programmed cell death 6-interacting protein
Synonyms Alix AIP1 Hp95
Synonyms name ALG-2 interacting protein X
Locus 3p22, 3
Discovery year 1999-12-10
GenBank acession BC020066
Entrez gene record 10015
Pubmed identfication 9880530
Havana BLAST/BLAT OTTHUMG00000130751

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