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ALK1 Antibody

ALK1 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenALK1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the ALK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis ALK1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P37023
PurityPurified
Description It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, Mutations in this gene are associated with hemorrhagic telangiectasia type 2, This protein, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, also known as Rendu-Osler-Weber syndrome 2, and a short C-terminal tail, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases, sometimes termed ALK1, ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands
ImmunogenA portion of amino acids 38-68 from the human protein was used as the immunogen for this ALK1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ALK1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetALK1
Short nameALK1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameALK1 (Antibody to)
Alternative techniqueantibodies
Identity 175
Gene ACVRL1
Long gene name activin A receptor like type 1
Synonyms gene ACVRLK1 ORW2
Synonyms gene name activin A receptor type II-like 1 activin A receptor type IL
Synonyms HHT2 ALK1 HHT
Locus 12q13, 13
Discovery year 1994-12-12
GenBank acession L17075
Entrez gene record 94
Pubmed identfication 8397373 8640225 22718755
RefSeq identity NM_000020
Classification Type 1 receptor serine/threonine kinases
Havana BLAST/BLAT OTTHUMG00000169507
Locus Specific Databases Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database LRG_543

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