| Long name | ALOX15B Primary Polyclonal Antibody |
| Also known as | ALOX15B PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ALOX15B |
| Specificity | This is a highly specific antibody against ALOX15B |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 5-55/676 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ALOX15B/15 Lipoxygenase 2 |
| Gene ID number | 247 |
| Swiss Prot | O15296 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE, Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE, Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S, May also regulate cytokine secretion by macrophages and therefore play a role in the immune response, May also regulate macrophage differentiation into proatherogenic foam cells, May regulate progression through the cell cycle and cell proliferation, 15S)-diHPETE, Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 15-LOX-B, 15-lipoxygenase 2, ALOX15B, Arachidonate 15-lipoxygenase B, Arachidonate 15-lipoxygenase type II, Linoleate 13-lipoxygenase 15-LOb, 15-LOX-2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ALOX15B |
| Short name | ALOX15B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | classification B (Antibody to), arachidonate 15-lipoxygenase |
| Alternative technique | antibodies |
| Alternative to gene target | 15-LOX-2, ALOX15B and IDBG-27642 and ENSG00000179593 and 247, ALOX15B and IDBG-635491 and ENSBTAG00000008779 and 286820, Alox8 and IDBG-190116 and ENSMUSG00000020891 and 11688, acting on single donors with incorporation of molecular oxygen, acting on single donors with incorporation of molecular oxygen, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, incorporation of two atoms of oxygen and also this GO :0036403: arachidonate 8(S)-lipoxygenase activity and also this GO :0046872: metal ion binding and also this GO :0050473: arachidonate 15-lipoxygenase activity, incorporation of two atoms of oxygen and molecular function this GO :0019369 and arachidonic acid metabolic process and biological process this GO :0019372 and lipoxygenase pathway and biological process this GO :0019898 and extrinsic component of membrane and cellular component this GO :0030336 and negative regulation of cell migration and biological process this GO :0030850 and prostate gland development and biological process this GO :0030856 and regulation of epithelial cell differentiation and biological process this GO :0035360 and positive regulation of peroxisome proliferator activated receptor signaling pathway and biological process this GO :0036403 and arachidonate 8(S)-lipoxygenase activity and molecular function this GO :0043651 and linoleic acid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045618 and positive regulation of keratinocyte differentiation and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045926 and negative regulation of growth and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050473 and arachidonate 15-lipoxygenase activity and molecular function this GO :0051122 and hepoxilin biosynthetic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0090197 and positive regulation of chemokine secretion and biological process, nuclei, oxidoreductase activity, this GO :0005506 and iron ion binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008289 and lipid binding and molecular function this GO :0010744 and positive regulation of macrophage derived foam cell differentiation and biological process this GO :0016020 and membrane and cellular component this GO :0016165 and lipoxygenase activity and molecular function this GO :0016702 and oxidoreductase activity, this GO :0005506: iron ion binding, this GO :0005506: iron ion binding and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008289: lipid binding and also this GO :0016165: lipoxygenase activity and also this GO :0016702: oxidoreductase activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008289: lipid binding, this GO :0016165: lipoxygenase activity, this GO :0016702: oxidoreductase activity, this GO :0036403: arachidonate 8(S)-lipoxygenase activity, this GO :0046872: metal ion binding, this GO :0050473: arachidonate 15-lipoxygenase activity, type B, arachidonate 15-lipoxygenase |
| Identity | 434 |
| Gene | ALOX15B |
| Long gene name | arachidonate 15-lipoxygenase, type B |
| Synonyms gene name | arachidonate 15-lipoxygenase, second type |
| Synonyms | 15-LOX-2 |
| Locus | 17p13, 1 |
| Discovery year | 1998-07-22 |
| GenBank acession | U78294 |
| Entrez gene record | 247 |
| Pubmed identfication | 9177185 |
| Classification | Arachidonate lipoxygenases |
| Havana BLAST/BLAT | OTTHUMG00000108181 |
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