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Alpha B Crystallin Antibody, ALEXA FLUOR 488

Alpha B Crystallin Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, Alpha B Crystallin Polyclonal Antibody
Also known asAnti-Alpha B Crystallin PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAlpha B Crystallin
SpecificityThis is a highly specific antibody against Alpha B Crystallin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Alpha B Crystallin
Gene ID Number1410
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Alpha and beta families are further divided into acidic and basic groups, Alpha crystallins are composed of two gene products: alpha-A and alpha-B, Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family, Alpha-A and alpha-B gene products are differentially expressed, Elevated expression of alpha-B crystallin occurs in many neurological diseases, Jul 2008], Mammalian lens crystallins are divided into alpha, Post-translational modifications decrease the ability to chaperone, Seven protein regions exist in crystallins: four homologous motifs, Since lens central fiber cells lose their nuclei during development, The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens, These heterogeneous aggregates consist of 30-40 subunits, They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture, [provided by RefSeq, a connecting peptide, a missense mutation cosegregated in a family with a desmin-related myopathy, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs, and N- and C-terminal extensions, and gamma families, and ubiquitous, beta, beta and gamma crystallins are also considered as a superfamily, for acidic and basic, instead they hold them in large soluble aggregates, making them extremely stable proteins, or enzyme, respectively, respectively, the alpha-A and alpha-B subunits have a 3:1 ratio, these crystallins are made and then retained throughout life, Crystallins are separated into two classes: taxon-specific
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms HSPB5
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Alpha B Crystallin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Description is a &alpha, - or alpha protein sometimes glycoprotein present in blood, The Alpha B Crystallin Antibody
Gene targetAlpha B Crystallin
Short nameAlpha B Crystallin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, a B Crystallin (Antibody to)
Alternative techniqueantibodies
Identity 2389
Gene CRYAB
Long gene name crystallin alpha B
Synonyms gene CRYA2
Synonyms gene name alpha B , crystallin
Locus 11q23, 1
Discovery year 1987-09-11
Entrez gene record 1410
Pubmed identfication 8431633
Classification Small heat shock proteins
Havana BLAST/BLAT OTTHUMG00000166885
Locus Specific Databases LOVD - Leiden Open Variation Database LRG_407

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