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ALS2/Alsin Antibody, ALEXA FLUOR 488

ALS2/Alsin Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, ALS2/Alsin Polyclonal Antibody
Also known asAnti-ALS2/Alsin PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenALS2/Alsin
SpecificityThis is a highly specific antibody against ALS2/Alsin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ALS2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Alsin acts as a guanine nucleotide exchange factor for Rab5, Alsin is a cytosolic protein that is associated with small, Alsin may mediate membrane transport events, The ALS2 C-terminal-like protein (ALS2CL) also modulates Rab 5 activity, The ALS2 gene encodes the Alsin protein, Therefore, a modulator of the endocytic pathway, a recessive form of amyotrophic lateral sclerosis (ALS2), and a form of complicated hereditary spastic paraplegia (cHSP), including juvenile primary lateral sclerosis (JPLS), infantile onset ascending hereditary spastic paralysis (IAHSP), potentially linking endocytic processes and actin cytoskeleton remodeling, punctate membrane structures, Mutations in the ALS2 gene result in a number of juvenile recessive motor neuron diseases (MNDs)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ALS2/Alsin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetALS2/Alsin
Short nameALS2/Alsin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, ALS2/Alsin (Antibody to)
Alternative techniqueantibodies
Identity 443
Gene ALS2
Long gene name ALS2, alsin Rho guanine nucleotide exchange factor
Synonyms gene ALS2CR6
Synonyms gene name amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 6 amyotrophic lateral sclerosis 2 (juvenile)
Synonyms name alsin
Locus 2q33, 1
Discovery year 1992-11-19
GenBank acession AB053305
Entrez gene record 57679
Pubmed identfication 11586298
RefSeq identity NM_020919
Classification Rho guanine nucleotide exchange factors VPS9 domain containing
Havana BLAST/BLAT OTTHUMG00000154507
Locus Specific Databases ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_654

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