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AMPK alpha 2 (Ser491) Antibody

AMPK alpha 2 (Ser491) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAMPK alpha 2 (Ser491) Antibody
Also known asAMPK alpha 2 (Ser491) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAMPK alpha 2 Ser491
SpecificityThis is a highly specific antibody against AMPK alpha 2 Ser491
Modification(s)Phosphorylation
Modification site(s)Ser491
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human AMPK alpha 2 around the phosphorylation site of Ser491
Gene ID number5563
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen AMPK is a heterotrimer consisting of an alpha catalytic subunit, AMPK is activated, AMPK is an important energy-sensing enzyme that monitors cellular energy status, In response to cellular metabolic stresses, Jul 2008], Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia, [provided by RefSeq, and non-catalytic beta and gamma subunits, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol, The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names , 5'-AMP-activated protein kinase catalytic subunit alpha-2, AAPK2_HUMAN, AMP activated protein kinase alpha 2 catalytic subunit, AMPK 2, AMPK alpha 2 chain, AMPK alpha 2 phospho Ser491, AMPK subunit alpha-2, AMPKalpha2, PRKAA, PRKAA 2, PRKAA2, Protein kinase AMP activated alpha 2 catalytic subunit, p-AMPK alpha 2 S491, p-AMPK alpha 2 Ser491, p-AMPK2phospho S491, AMPK alpha 2 phospho S491
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAMPK alpha 2 (Ser491)
Short nameAMPK alpha 2 (Ser491) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAMPK a 2 (Ser491) (Antibody to)
Alternative techniqueantibodies
Identity 9377
Gene PRKAA2
Long gene name protein kinase AMP-activated catalytic subunit alpha 2
Synonyms gene PRKAA
Synonyms gene name AMP-activated, alpha 2 catalytic subunit , protein kinase
Synonyms AMPK AMPKa2
Locus 1p32, 2
Discovery year 1995-12-12
GenBank acession BC069823
Entrez gene record 5563
Pubmed identfication 7959015
RefSeq identity NM_006252
Havana BLAST/BLAT OTTHUMG00000008282

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