Name : AMPK alpha 2 (Ser491) Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN3345444735
| Long name | Cy3 Conjugated, AMPK alpha 2 (Ser491) Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | AMPK alpha 2 Ser491 |
| Specificity | This is a highly specific antibody against AMPK alpha 2 Ser491 |
| Modification | Phosphorylation |
| Modification site | Ser491 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human AMPK alpha 2 around the phosphorylation site of Ser491 |
| Gene ID number | 5563 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | AMPK is a heterotrimer consisting of an alpha catalytic subunit, AMPK is activated, AMPK is an important energy-sensing enzyme that monitors cellular energy status, In response to cellular metabolic stresses, Jul 2008], Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia, [provided by RefSeq, and non-catalytic beta and gamma subunits, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol, The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | AMPK AMPKa2 |
| Properties | 1 of the AMPK alpha 2 (Ser491) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | AMPK alpha 2 (Ser491) Conjugated |
| Short name | Conjugated, AMPK alpha 2 (Ser491) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, AMPK a 2 (Ser491) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9377 |
| Gene | PRKAA2 |
| Long gene name | protein kinase AMP-activated catalytic subunit alpha 2 |
| Synonyms gene | PRKAA |
| Synonyms gene name | AMP-activated, alpha 2 catalytic subunit , protein kinase |
| Locus | 1p32, 2 |
| Discovery year | 1995-12-12 |
| GenBank acession | BC069823 |
| Entrez gene record | 5563 |
| Pubmed identfication | 7959015 |
| RefSeq identity | NM_006252 |
| Havana BLAST/BLAT | OTTHUMG00000008282 |