Name : AMPK beta 1 + 2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9168687251
| Long name | AMPK beta 1 + 2 Primary Polyclonal Antibody |
| Also known as | AMPK beta 1 + 2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | AMPK beta 1 + 2 |
| Specificity | This is a highly specific antibody against AMPK beta 1 + 2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 238-270/270 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AMPK beta 1 |
| Gene ID number | 5564 |
| Swiss Prot | Q9Y478 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, AMPK acts via direct phosphorylation of metabolic enzymes, Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, In response to reduction of intracellular ATP levels, PRKAG2 or PRKAG3), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism, and by longer-term effects via phosphorylation of transcription regulators, as well as cell growth and proliferation, carbohydrate and lipid biosynthesis, probably by indirectly activating myosin, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, Non-catalytic subunit of AMP-activated protein kinase (AMPK) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 5'-AMP-activated protein kinase subunit beta-1, AMPK subunit beta-1, AMPKb, HAMPKb, PRKAB1, AMPK |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | AMPK beta 1 + 2 |
| Short name | AMPK beta 1 + 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | AMPK b 1 and 2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9377 |
| Gene | PRKAA2 |
| Long gene name | protein kinase AMP-activated catalytic subunit alpha 2 |
| Synonyms gene | PRKAA |
| Synonyms gene name | AMP-activated, alpha 2 catalytic subunit , protein kinase |
| Synonyms | AMPK AMPKa2 |
| Locus | 1p32, 2 |
| Discovery year | 1995-12-12 |
| GenBank acession | BC069823 |
| Entrez gene record | 5563 |
| Pubmed identfication | 7959015 |
| RefSeq identity | NM_006252 |
| Havana BLAST/BLAT | OTTHUMG00000008282 |