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AMPK beta 1 + 2 Antibody, FITC Conjugated

AMPK beta 1 + 2 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, AMPK beta 1 + 2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAMPK beta 1 + 2
SpecificityThis is a highly specific antibody against AMPK beta 1 + 2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range238-270/270
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human AMPK beta 1
Gene ID number5564
Swiss ProtQ9Y478
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, AMPK acts via direct phosphorylation of metabolic enzymes, Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, In response to reduction of intracellular ATP levels, PRKAG2 or PRKAG3), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism, and by longer-term effects via phosphorylation of transcription regulators, as well as cell growth and proliferation, carbohydrate and lipid biosynthesis, probably by indirectly activating myosin, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, Non-catalytic subunit of AMP-activated protein kinase (AMPK)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms AMPK AMPKa2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAMPK beta 1 + 2 Conjugated
Short name FITC Conjugated, AMPK beta 1 + 2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, AMPK b 1 and 2 (Antibody to)
Alternative techniqueantibodies
Identity 9377
Gene PRKAA2
Long gene name protein kinase AMP-activated catalytic subunit alpha 2
Synonyms gene PRKAA
Synonyms gene name AMP-activated, alpha 2 catalytic subunit , protein kinase
Locus 1p32, 2
Discovery year 1995-12-12
GenBank acession BC069823
Entrez gene record 5563
Pubmed identfication 7959015
RefSeq identity NM_006252
Havana BLAST/BLAT OTTHUMG00000008282

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