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AMPK gamma 3/PRKAG3 Antibody

AMPK gamma 3/PRKAG3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAMPK gamma 3/PRKAG3 Primary Polyclonal Antibody
Also known asAMPK gamma 3/PRKAG3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAMPK gamma 3/PRKAG3
SpecificityThis is a highly specific antibody against AMPK gamma 3/PRKAG3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range174-220/489
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AMPK gamma 3
Gene ID number53632
Swiss ProtQ9UGI9
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ADP also stimulates phosphorylation, ADP and ATP, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, AMPK acts via direct phosphorylation of metabolic enzymes, ATP promotes dephosphorylation of catalytic subunit, Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, Gamma non-catalytic subunit mediates binding to AMP, In response to reduction of intracellular ATP levels, an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism, and by longer-term effects via phosphorylation of transcription regulators, as well as cell growth and proliferation, carbohydrate and lipid biosynthesis, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits, probably by indirectly activating myosin, rendering the AMPK enzyme inactive, without stimulating already phosphorylated catalytic subunit, AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 5'-AMP-activated protein kinase subunit gamma-3, AMPK gamma3, AMPK subunit gamma-3, PRKAG3, AMPKG3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAMPK gamma 3/PRKAG3
Short nameAMPK gamma 3/PRKAG3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name AMP-activated, g 3 non-catalytic subunit (Antibody to), AMPK g 3/protein phosphorylation catalyst
Alternative techniqueantibodies
Alternative to gene target AMP-activated, Extracellular, PRKAG3 and IDBG-643891 and ENSBTAG00000013492 and 511961, PRKAG3 and IDBG-81160 and ENSG00000115592 and 53632, Prkag3 and IDBG-168633 and ENSMUSG00000006542 and 241113, adenyl nucleotide binding, gamma 3 non-catalytic subunit, this GO :0004679 and AMP-activated protein kinase activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005829 and cytosol and cellular component this GO :0005978 and glycogen biosynthetic process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006633 and fatty acid biosynthetic process and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0015758 and glucose transport and biological process this GO :0016301 and kinase activity and molecular function this GO :0016310 and phosphorylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030554 and adenyl nucleotide binding and molecular function this GO :0031588 and AMP-activated protein kinase complex and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0061024 and membrane organization and biological process, this GO :0004679: AMP-activated protein kinase activity, this GO :0004679: AMP-activated protein kinase activity and also this GO :0005524: ATP binding and also this GO :0016301: kinase activity and also this GO :0019901: protein kinase binding and also this GO :0030554: adenyl nucleotide binding, this GO :0005524: ATP binding, this GO :0016301: kinase activity, this GO :0019901: protein kinase binding, this GO :0030554: adenyl nucleotide binding, protein kinase
Identity 9387
Gene PRKAG3
Long gene name protein kinase AMP-activated non-catalytic subunit gamma 3
Synonyms gene name AMP-activated, gamma 3 non-catalytic subunit , protein kinase
Locus 2q35
Discovery year 2000-07-31
GenBank acession AF214519
Entrez gene record 53632
Pubmed identfication 10818001
Havana BLAST/BLAT OTTHUMG00000133078

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